Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10362667 | 0.90 | NR4A2 (0.44) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| SCHEMBL10362599 | 0.89 | KMT2A (0.46) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| SCHEMBL10363062 | 0.87 | GABRA1 (0.62) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| SCHEMBL10362899 | 0.85 | LMNA (0.46) | TSHRLMNAALDH1A1HSD17B10KDM4E | |
| SCHEMBL10364135 | 0.83 | GABRA1 (0.49) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| SCHEMBL922165 | 0.81 | TSHR (0.53) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| SCHEMBL3125776 | 0.80 | CYP3A4 (0.59) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| SCHEMBL10362900 | 0.79 | PPARA (0.45) | TSHRLMNAALDH1A1GABRA1GABRB2 | |
| SCHEMBL3193263 | 0.75 | ABL1 (0.41) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| SCHEMBL8828941 | 0.75 | GABRA1 (0.44) | TSHRALDH1A1HSD17B10GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010225-B1 | NEGATIVELY WORKING PHOTOCROSSLINKABLE LAYERS DEVELOPABLE WITH AQUEOUS ALKALINE SOLUTIONS | Agfa-Gevaert AG (DE) | 1981-11-25 | — | — | EP | disclosed |
| EP-0010225-A2 | Negatively working photocrosslinkable layers developable with aqueous alkaline solutions | Agfa-Gevaert AG (DE) | 1980-04-30 | — | — | EP | disclosed |