Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 2/20 | 0.63 |
| ▸ | ALPI | P09923 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.58 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.57 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nafimidone SCHEMBL1817018 | 0.97 | ALPG (0.66) | ALPGALPITDP1PLAAL3MBTL1 | |
| Nafimidone SCHEMBL29861032 | 0.96 | ALPG (0.67) | ALPGALPITDP1PLAAL3MBTL1 | |
| Nafimidone SCHEMBL412582 | 0.96 | ALPG (0.67) | ALPGALPITDP1PLAAL3MBTL1 | |
| Nafimidone SCHEMBL11355091 | 0.92 | ALPG (0.57) | ALPGALPITDP1PLAAL3MBTL1 | |
| SCHEMBL11481042 | 0.85 | ALPG (0.68) | ALPGALPITDP1PLAAL3MBTL1 | |
| Ethylene SCHEMBL10973442 | 0.85 | ALPG (0.57) | ALPGALPITDP1PLAAL3MBTL1 | |
| SCHEMBL11253238 | 0.84 | TBXAS1 (0.56) | ALPGALPITDP1PLAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL11181980 | 0.84 | ALPG (0.69) | ALPGALPITDP1PLAAL3MBTL1 | |
| SCHEMBL11188512 | 0.84 | ALPG (0.63) | ALPGALPITDP1PLAAL3MBTL1 | |
| SCHEMBL11474959 | 0.84 | ALPG (0.63) | ALPGALPITDP1PLAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001926-B1 | 1-(NAPHTHYLETHYL)IMIDAZOLE DERIVATIVES, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYNTEX (U.S.A.) INC. (US) | 1981-04-29 | — | — | EP | disclosed |
| EP-0001926-A1 | 1-(Naphthylethyl)imidazole derivatives, their preparation, and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1979-05-16 | — | — | EP | disclosed |
| US-4150153-A | ANTICONVULSANTS, GASTRIC ANTISECRETORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1979-04-17 | — | — | US | disclosed |