Carbon Monoxide

Carbon Monoxide

SCHEMBL11357166

NCCCP(c1ccccc1)c1ccccc1.NCCCP(c1ccccc1)c1ccccc1.NCCCP(c1ccccc1)c1ccccc1.[C]=O.[H-].[H-].[H-].[Rh+3]

nearest known ligand 0.38

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Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.36
HTR2A P28223 3/20 0.35
HRH1 P35367 1/20 0.35
KIF11 P52732 1/20 0.34
CYP2A6 P11509 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
LOXL2 Q9Y4K0 1/20 0.31
CYP3A4 P08684 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
POLB P06746 1/20 0.31
ADRA2C P18825 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbon Monoxide SCHEMBL10733895 0.94 MAOA (0.38) MAOAHTR2AHRH1KIF11CYP2A6
SCHEMBL474417 0.90 MAOA (0.43) MAOAHTR2AHRH1KIF11CYP2A6
SCHEMBL27716064 0.88 MAOA (0.41) MAOAHTR2AHRH1KIF11CYP2A6
Formaldehyde SCHEMBL11357169 0.86 MAOA (0.38) MAOAHTR2AHRH1KIF11CYP2A6
SCHEMBL28858586 0.84 MAOA (0.46) MAOAHTR2AHRH1KIF11CYP2A6
SCHEMBL3325910 0.82 MAOA (0.38) MAOAHTR2AHRH1KIF11CYP2A6
SCHEMBL28964148 0.82 MAOA (0.45) MAOAHTR2AHRH1KIF11CYP2A6
Carbon Monoxide SCHEMBL11679960 0.81 CYP3A4 (0.38) CYP3A4TDP1
Allylamine SCHEMBL11350886 0.79 MAOA (0.35) MAOAHTR2AHRH1KIF11CYP2A6
SCHEMBL474250 0.77 CYP3A4 (0.41) MAOAHTR2AHRH1KIF11CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0024091-A4 HYDROFORMYLATION PROCESS AND NOVEL TRANSITION METAL CATALYSTS. EXXON RESEARCH ENGINEERING CO (US) 1981-07-16 EP disclosed
EP-0024091-A1 HYDROFORMYLATION PROCESS AND NOVEL TRANSITION METAL CATALYSTS. EXXON RESEARCH ENGINEERING CO (US) 1981-02-25 EP disclosed
WO-1980001690-A1 CARBONYLATION PROCESS AND NOVEL TRANSITION METAL CATALYSTS EXXON RESEARCH ENGINEERING CO (US) 1980-08-21 WO disclosed