Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL474417 | 0.92 | MAOA (0.43) | MAOAHTR2AHRH1KIF11SMN1; SMN2 | |
| SCHEMBL27716064 | 0.90 | MAOA (0.41) | MAOAHTR2AHRH1KIF11SMN1; SMN2 | |
| SCHEMBL1767611 | 0.88 | CYP3A4 (0.35) | MAOAHTR2AHRH1SMN1; SMN2CYP2A6 | |
| SCHEMBL1466232 | 0.88 | CYP3A4 (0.35) | MAOAHTR2AHRH1SMN1; SMN2CYP2A6 | |
| SCHEMBL19946522 | 0.87 | CYP3A4 (0.38) | TDP1CYP3A4 | |
| SCHEMBL28858586 | 0.85 | MAOA (0.46) | MAOAHTR2AHRH1KIF11SMN1; SMN2 | |
| Formaldehyde SCHEMBL11357169 | 0.84 | MAOA (0.38) | MAOAHTR2AHRH1KIF11SMN1; SMN2 | |
| Carbon Monoxide SCHEMBL10733895 | 0.84 | MAOA (0.38) | MAOAHTR2AHRH1KIF11SMN1; SMN2 | |
| SCHEMBL28964148 | 0.83 | MAOA (0.45) | MAOAHTR2AHRH1KIF11SMN1; SMN2 | |
| SCHEMBL29531328 | 0.83 | CYP3A4 (0.41) | TDP1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1868964-B1 | HYDROGENATION OF ESTERS WITH RU/BIDENTATE LIGANDS COMPLEXES | FIRMENICH & CIE (CH) | 2016-11-23 | — | — | EP | disclosed |
| WO-2013041106-A1 | SYSTEM PROVIDING CONTROLLED DELIVERY OF GASEOUS 11CO FOR CARBONYLATION REACTIONS IN THE PREPARATION OF RADIOPHARMACEUTICALS FOR PET IMAGING | AARHUS UNIVERSITET (DK) | 2013-03-28 | — | — | WO | disclosed |
| WO-2012079583-A1 | SYSTEM PROVIDING CONTROLLED DELIVERY OF GASEOUS CO FOR CARBONYLATION REACTIONS | AARHUS UNIVERSITET (DK) | 2012-06-21 | — | — | WO | disclosed |
| US-20100280273-A1 | HYDROGENATION OF ESTERS WITH RU/BIDENTATE LIGANDS COMPLEXES | FIRMENICH SA (CH) | 2010-11-04 | — | — | US | disclosed |
| US-7763758-B2 | Complex containing amino or imino groups with phosphino group | FIRMENICH SA (CH) | 2010-07-27 | — | — | US | disclosed |
| US-20100130754-A1 | HYDROGENATION OF ESTERS WITH RU/BIDENTATE LIGANDS COMPLEXES | FIRMENICH SA | 2010-05-27 | — | — | US | disclosed |
| US-20080071121-A1 | Complex containing amino or imino groups with phosphino group | FIRMENICH SA (CH) | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130754-A1 | HYDROGENATION OF ESTERS WITH RU/BIDENTATE LIGANDS COMPLEXES | ADH5, ADH1A, ADH1C | MAOA 3533/4885HTR2A 4137/4885HRH1 188/4885 |
| US-20080071121-A1 | Complex containing amino or imino groups with phosphino group | ADH1C, ADH5, PHOSPHO1 | MAOA 2918/4885HTR2A 4055/4885HRH1 1045/4885 |
| US-20100280273-A1 | HYDROGENATION OF ESTERS WITH RU/BIDENTATE LIGANDS COMPLEXES | ADH5, ADH1A, ADH1C | MAOA 3533/4885HTR2A 4137/4885HRH1 188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.