Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 14/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | IKBKE | Q14164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11102213 | 0.88 | RAB9A (0.46) | TBK1RAB9AIKBKEKDM4EGAA | |
| SCHEMBL11354810 | 0.87 | RAB9A (0.60) | TBK1RAB9AKDM4EGAANPC1 | |
| SCHEMBL11361695 | 0.86 | TBK1 (0.60) | TBK1RAB9AIKBKEKDM4EGAA | |
| SCHEMBL11126292 | 0.86 | RAB9A (0.45) | TBK1RAB9AIKBKEKDM4EGAA | |
| SCHEMBL17548698 | 0.86 | TBK1 (0.74) | TBK1RAB9AIKBKEKDM4EGAA | |
| SCHEMBL11108156 | 0.85 | MAOB (0.56) | TBK1RAB9AKDM4EGAANPC1 | |
| SCHEMBL11098818 | 0.85 | RAB9A (0.44) | TBK1RAB9AIKBKEKDM4EGAA | |
| SCHEMBL2901850 | 0.85 | TBK1 (0.72) | TBK1RAB9AIKBKEKDM4EGAA | |
| SCHEMBL11356293 | 0.84 | MAOB (0.54) | TBK1RAB9AKDM4EGAANPC1 | |
| SCHEMBL11098817 | 0.84 | RAB9A (0.43) | TBK1RAB9AIKBKEKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4299963-A | ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-11-10 | — | — | US | claimed |