Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11377863 | 0.98 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2GSK3AGSK3BPOLB | |
| SCHEMBL11359145 | 0.98 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2GSK3AGSK3BPOLB | |
| SCHEMBL11359810 | 0.96 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2GSK3AGSK3BPOLB | |
| SCHEMBL11370972 | 0.91 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2GSK3AGSK3BPOLB | |
| SCHEMBL11368074 | 0.87 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2GSK3AGSK3BPOLB | |
| SCHEMBL11358886 | 0.86 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2GSK3AGSK3BPOLB | |
| SCHEMBL11377938 | 0.86 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2GSK3AGSK3BPOLB | |
| SCHEMBL11365858 | 0.83 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2GSK3AGSK3BPOLB | |
| SCHEMBL11365262 | 0.83 | GSK3A (0.46) | ALDH1A1SMN1; SMN2GSK3AGSK3BPOLB | |
| SCHEMBL9623389 | 0.82 | POLB (0.56) | ALDH1A1SMN1; SMN2GSK3AGSK3BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4249934-A | 1,2-Alkylene-4-substituted urazole herbicides | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1981-02-10 | — | — | US | claimed |
| JP-52083687-A | — | — | None | — | — | JP | disclosed |
| US-4249934-A | 1,2-Alkylene-4-substituted urazole herbicides | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1981-02-10 | — | — | US | disclosed |
| JP-S5283687-A | 1,2-ALKYLENE-4-SUBSTITUTED URAZOL | MITSUBISHI CHEM IND LTD | 1977-07-12 | — | — | JP | disclosed |