SCHEMBL11370972

SCHEMBL11370972

O=c1n(-c2ccc(Cl)cc2)c(=O)n2n1CC2

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
GSK3A P49840 1/20 0.48
GSK3B P49841 1/20 0.48
POLB P06746 2/20 0.48
ALOX5 P09917 2/20 0.46
MGLL Q99685 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
HTR3E A5X5Y0 1/20 0.42
HTR3B O95264 1/20 0.42
ADRB1 P08588 1/20 0.42
HTR3A P46098 1/20 0.42
HTR3D Q70Z44 1/20 0.42
HTR3C Q8WXA8 1/20 0.42
SIGMAR1 Q99720 1/20 0.42
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.41
ELANE P08246 1/20 0.41
TSHR P16473 2/20 0.41
KDM4E B2RXH2 1/20 0.40
CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11359810 0.91 ALDH1A1 (0.65) ALDH1A1GSK3AGSK3BPOLBALOX5
SCHEMBL11358737 0.91 ALDH1A1 (0.59) ALDH1A1GSK3AGSK3BPOLBALOX5
SCHEMBL11359145 0.90 ALDH1A1 (0.58) ALDH1A1GSK3AGSK3BPOLBALOX5
SCHEMBL11377863 0.90 ALDH1A1 (0.58) ALDH1A1GSK3AGSK3BPOLBALOX5
SCHEMBL9623389 0.85 POLB (0.56) ALDH1A1GSK3AGSK3BPOLBALOX5
SCHEMBL11622087 0.85 ALDH1A1 (0.45) ALDH1A1GSK3AGSK3BPOLBALOX5
SCHEMBL11365262 0.83 GSK3A (0.46) ALDH1A1GSK3AGSK3BPOLBALOX5
SCHEMBL11365858 0.79 ALDH1A1 (0.51) ALDH1A1GSK3AGSK3BPOLBALOX5
SCHEMBL11368074 0.79 ALDH1A1 (0.47) ALDH1A1GSK3AGSK3BPOLBALOX5
SCHEMBL11370185 0.79 LMNA (0.42) ALDH1A1GSK3AGSK3BPOLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4249934-A 1,2-Alkylene-4-substituted urazole herbicides MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) 1981-02-10 US disclosed