SCHEMBL1135904

SCHEMBL1135904

N#CC[C@@H](O)C[C@@H](O)CC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.50
GABRR1 P24046 2/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.39
MMP12 P39900 3/20 0.36
MMP13 P45452 3/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
GPR84 Q9NQS5 4/20 0.35
TDP1 Q9NUW8 1/20 0.32
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30
MMP14 P50281 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4739671 1.00 SLC22A6 (0.50) SLC22A6GABRR1LMNAMAPTMMP12
SCHEMBL17204383 1.00 SLC22A6 (0.50) SLC22A6GABRR1LMNAMAPTMMP12
SCHEMBL6951133 1.00 SLC22A6 (0.50) SLC22A6GABRR1LMNAMAPTMMP12
SCHEMBL17203945 1.00 SLC22A6 (0.50) SLC22A6GABRR1LMNAMAPTMMP12
SCHEMBL197015 0.89
SCHEMBL198166 0.89
SCHEMBL197016 0.89
SCHEMBL6928974 0.86 SLC22A6 (0.55) SLC22A6GABRR1LMNAMAPTMMP12
SCHEMBL6928104 0.86 SLC22A6 (0.55) SLC22A6GABRR1LMNAMAPTMMP12
SCHEMBL6928106 0.86 SLC22A6 (0.55) SLC22A6GABRR1LMNAMAPTMMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118562779-A Stable halohydrin dehalogenase freeze-dried powder preparation and application thereof 浙江乐普药业股份有限公司 2024-08-30 CN claimed
CN-107653238-B Carbonyl reductase gene engineering bacterium immobilized cell and application thereof 浙江工业大学 2021-05-11 CN claimed
CN-110387359-B Carbonyl reductase mutant and application thereof 湖州颐盛生物科技有限公司 2021-04-20 CN claimed
CN-109055327-B Aldehyde ketone reductase mutant and application thereof 浙江工业大学 2021-04-06 CN claimed
CN-110004120-B Recombinant aldone reductase mutant and application thereof 浙江工业大学 2021-02-02 CN claimed
CN-111778223-A Method for modifying stereoselectivity of carbonyl reductase, carbonyl reductase mutant and application 浙江工业大学 2020-10-16 CN claimed
US-10724008-B2 Ketoreductases C-LECTA GMBH (DE) 2020-07-28 US claimed
EP-3134519-B1 KETOREDUCTASES C LECTA GMBH (DE) 2018-06-06 EP claimed
US-20170218345-A1 KETOREDUCTASES C-LECTA GMBH (DE) 2017-08-03 US claimed
EP-3134519-A1 KETOREDUCTASES c-LEcta GmbH (DE) 2017-03-01 EP claimed
WO-2015162064-A1 KETOREDUCTASES C-LECTA GMBH (DE) 2015-10-29 WO claimed
EP-1054860-B1 PROCESS FOR THE SYNTHESIS OF 1,3-DIOLS PFIZER IRELAND PHARMACEUTICALS (IE) 2007-04-25 EP claimed
EP-1625223-A2 CHEMOENZYMATIC METHODS FOR THE SYNTHESIS OF STATINS AND STATIN INTERMEDIATES Diversa Corporation (US) 2006-02-15 EP claimed
WO-2004027075-A2 CHEMOENZYMATIC METHODS FOR THE SYNTHESIS OF STATINS AND STAIN INTERMEDIATES DIVERSA CORPORATION (US) 2004-04-01 WO claimed
EP-1077212-B1 PROCESS FOR PRODUCING 6-CYANOMETHYL-1,3-DIOXANE-4-ACETIC ACID DERIVATIVES KANEKA CORP (JP) 2003-08-20 EP claimed
EP-1077212-A1 PROCESS FOR PRODUCING 6-CYANOMETHYL-1,3-DIOXANE-4-ACETIC ACID DERIVATIVES KANEKA CORPORATION (JP) 2001-02-21 EP claimed
CN-120485143-A Carbonyl reductase mutant and application thereof in synthesizing statin drug intermediate 浙江工业大学 2025-08-15 CN disclosed
CN-118562779-A Stable halohydrin dehalogenase freeze-dried powder preparation and application thereof 浙江乐普药业股份有限公司 2024-08-30 CN disclosed
WO-2002096915-A1 PROCESS FOR PRODUCING OPTICALLY PURE Δ - HYDROXY-Β -KETOESTER DERIVATIVES SAMSUNG FINE CHEMICALS CO., LTD. (KR) 2002-12-05 WO disclosed
EP-1077212-A1 PROCESS FOR PRODUCING 6-CYANOMETHYL-1,3-DIOXANE-4-ACETIC ACID DERIVATIVES KANEKA CORPORATION (JP) 2001-02-21 EP disclosed