Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 5/20 | 0.46 |
| ▸ | ADH1B | P00325 | 1/20 | 0.44 |
| ▸ | ADH1C | P00326 | 1/20 | 0.44 |
| ▸ | ADH1A | P07327 | 1/20 | 0.44 |
| ▸ | ADH4 | P08319 | 1/20 | 0.44 |
| ▸ | ADH7 | P40394 | 1/20 | 0.44 |
| ▸ | DNM2 | P50570 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11366375 | 1.00 | DNM1 (0.46) | DNM1ADH1BADH1CADH1AADH4 | |
| SCHEMBL11363758 | 1.00 | DNM1 (0.46) | DNM1ADH1BADH1CADH1AADH4 | |
| SCHEMBL17655887 | 0.92 | DNM1 (0.39) | DNM1ADH1BADH1CADH1AADH4 | |
| SCHEMBL24104281 | 0.91 | DNM1 (0.50) | DNM1ADH1BADH1CADH1AADH4 | |
| SCHEMBL13762880 | 0.81 | ADH1B (0.52) | DNM1ADH1BADH1CADH1AADH4 | |
| SCHEMBL25072163 | 0.81 | ADH1B (0.52) | DNM1ADH1BADH1CADH1AADH4 | |
| SCHEMBL18546867 | 0.81 | ADH1B (0.52) | DNM1ADH1BADH1CADH1AADH4 | |
| SCHEMBL5011942 | 0.81 | ADH1B (0.52) | DNM1ADH1BADH1CADH1AADH4 | |
| SCHEMBL9214863 | 0.81 | ADH1B (0.52) | DNM1ADH1BADH1CADH1AADH4 | |
| SCHEMBL24104636 | 0.81 | ADH1B (0.52) | DNM1ADH1BADH1CADH1AADH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260770-A | Naphtholactam dyes | CIBA-GEIGY AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
| US-4083847-A | Transiently water-soluble disperse mono-azo dyes containing a diamino-methylene-carbacyl group | CIBA-GEIGY CORPORATION (US) | 1978-04-11 | — | — | US | disclosed |