Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | UGT2B7 | P16662 | 2/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22953394 | 0.81 | APLNR (0.41) | UGT2B7SLC22A6SMN1; SMN2ALDH1A1GLA | |
| SCHEMBL76317 | 0.73 | TDP1 (0.36) | TSHRNFKB1CYP2C19 | |
| SCHEMBL9338828 | 0.73 | TSHR (0.46) | TSHRNFKB1CYP2C19 | |
| SCHEMBL9879415 | 0.72 | TDP1 (0.47) | TSHRNFKB1CYP2C19 | |
| SCHEMBL28247100 | 0.72 | FFAR4 (0.40) | TSHRNFKB1ALDH1A1GPR84 | |
| SCHEMBL11153675 | 0.71 | TSHR (0.41) | TSHRNFKB1CYP2C19 | |
| SCHEMBL27558706 | 0.71 | CYP1A2 (0.40) | TSHRNFKB1CYP2C19 | |
| SCHEMBL6694522 | 0.70 | CYP1A2 (0.37) | TSHRNFKB1CYP2C19GPR84 | |
| SCHEMBL11606230 | 0.70 | TSHR (0.37) | TSHRNFKB1CYP2C19 | |
| SCHEMBL30644788 | 0.70 | CYP2D6 (0.38) | TSHRNFKB1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4256627-A | COMPRISING COMPLEXES OF POLYMERS HAVING UNITS CONTAINING ALKYLPIPERIDINE GROUPS AND NICKEL OR COBALT CARBOXYLATES OR ENOLATES | CIBA-GEIGY CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |