SCHEMBL11359809

SCHEMBL11359809

COc1cc(OC)cc(C(=O)C=C2OC(=O)c3ccccc32)c1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
ALDH1A1 P00352 2/20 0.47
MAPT P10636 2/20 0.47
KDM4E B2RXH2 1/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ABCG2 Q9UNQ0 1/20 0.47
TSHR P16473 1/20 0.43
MAPK1 P28482 1/20 0.43
USP2 O75604 1/20 0.42
PKM P14618 1/20 0.42
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11366511 0.89 MAOB (0.52) KMT2AMEN1ALDH1A1MAPTKDM4E
SCHEMBL10779318 0.87 ALDH1A1 (0.49) KMT2AMEN1ALDH1A1MAPTKDM4E
SCHEMBL11627151 0.81 CDC25A (0.48) KMT2AMEN1ALDH1A1MAPTNPC1
SCHEMBL11351914 0.81 TNFRSF1A (0.52) KMT2AMEN1ALDH1A1MAPTKDM4E
SCHEMBL11363960 0.79 NTSR1 (0.64) KMT2AMEN1ALDH1A1MAPTKDM4E
SCHEMBL11357428 0.79 NTSR1 (0.52) KMT2AMEN1ALDH1A1MAPTKDM4E
SCHEMBL10717055 0.78 ALDH1A1 (0.55) KMT2AMEN1ALDH1A1KDM4EL3MBTL1
SCHEMBL10779310 0.76 ALDH1A1 (0.59) KMT2AMEN1ALDH1A1MAPTKDM4E
SCHEMBL11366044 0.75 ABCG2 (0.50) KMT2AMEN1ALDH1A1MAPTKDM4E
SCHEMBL11359116 0.75 POLB (0.49) KMT2AMEN1ALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4255181-A Use of substituted-3-phenacylidenephthalides as corn plant growth regulants MONSANTO COMPANY (US) 1981-03-10 US disclosed
US-4182622-A REDUCE HERBICIDAL INJURY TO RICE PLANTS MONSANTO COMPANY (US) 1980-01-08 US disclosed
US-4129729-A PLANT GROWTH REGULATORS MONSANTO COMPANY (US) 1978-12-12 US disclosed