Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10415303 | 0.87 | ITGB1 (0.40) | RIPK1 | |
| SCHEMBL10937132 | 0.83 | BRD4 (0.43) | — | |
| SCHEMBL11205142 | 0.83 | BRD4 (0.43) | — | |
| SCHEMBL4098581 | 0.81 | BRD4 (0.34) | — | |
| SCHEMBL4098576 | 0.81 | BRD4 (0.34) | — | |
| SCHEMBL5156976 | 0.81 | BRD4 (0.34) | — | |
| SCHEMBL6963835 | 0.80 | — | — | |
| SCHEMBL10660255 | 0.80 | — | — | |
| SCHEMBL6963830 | 0.80 | — | — | |
| SCHEMBL11005101 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273709-A | Process for the preparation of thienamycin and intermediates | MERCK & CO., INC. (US) | 1981-06-16 | — | — | US | disclosed |
| EP-0026817-A1 | Preparation of azetidin-2-ones suitable for the synthesis of thienamycin and azetidin-2-ones useful in a synthesis of that kind | MERCK & CO. INC. (US) | 1981-04-15 | — | — | EP | disclosed |