Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 7/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10937132 | 1.00 | BRD4 (0.43) | BRD4ALDH1A1NPSR1MIFHDAC6 | |
| SCHEMBL10415303 | 0.83 | ITGB1 (0.40) | POLB | |
| SCHEMBL11360693 | 0.83 | MT-CO2 (0.33) | — | |
| SCHEMBL10414651 | 0.79 | GLA (0.43) | ALDH1A1L3MBTL1HTT | |
| SCHEMBL5156976 | 0.78 | BRD4 (0.34) | BRD4 | |
| SCHEMBL4098581 | 0.78 | BRD4 (0.34) | BRD4 | |
| SCHEMBL6963830 | 0.76 | — | — | |
| SCHEMBL10660255 | 0.76 | — | — | |
| SCHEMBL6963835 | 0.76 | — | — | |
| SCHEMBL11005101 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0091239-A1 | Azetidine derivatives and a process for their production | KOWA COMPANY, LTD. (JP) | 1983-10-12 | — | — | EP | disclosed |