SCHEMBL1136159

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1135964	0.92	MAOB (0.39)	MAOBBRDTMTNR1AMTNR1BMET
	SCHEMBL1136104	0.91	PDE4D (0.37)	MAOBBRDTMTNR1AMTNR1BMET
	SCHEMBL1136374	0.90	EGFR (0.38)	MAOBMTNR1AMTNR1BALDH1A1
	SCHEMBL1136189	0.89	MAOB (0.37)	MAOBBRDTMTNR1AMTNR1BMET
	SCHEMBL1136156	0.86	MDM2 (0.36)	MAOBBRDTMTNR1AMTNR1BMET
	SCHEMBL1136119	0.86	MAOB (0.40)	MAOBMETKDRAXLALDH1A1
	SCHEMBL1136089	0.84	PDE4D (0.36)	MAOBFFAR1ALDH1A1PKMMAOA
	SCHEMBL2430551	0.83	BRDT (0.39)	BRDTMTNR1AMTNR1BALDH1A1CRHR1
	SCHEMBL1136355	0.82	PDE4D (0.36)	MAOBALDH1A1PKMCRHR1MAOA
	SCHEMBL1136151	0.82	ADORA3 (0.44)	BRDTMETKDRALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.