Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 14/20 | 0.45 |
| ▸ | RAB9A | P51151 | 14/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.45 |
| ▸ | HPGD | P15428 | 8/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.43 |
| ▸ | TP53 | P04637 | 7/20 | 0.43 |
| ▸ | PKM | P14618 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | METAP2 | P50579 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | METAP1 | P53582 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL824391 | 0.78 | NPC1 (0.60) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL26827776 | 0.72 | NPC1 (0.53) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL227743 | 0.67 | NPC1 (0.78) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL28865125 | 0.66 | METAP1 (0.58) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL6642970 | 0.66 | RAB9A (0.51) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL82498 | 0.66 | NPC1 (0.58) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL4791411 | 0.66 | NPC1 (0.56) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL8327904 | 0.65 | RAB9A (0.44) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL20677815 | 0.65 | NPC1 (0.75) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL17452040 | 0.65 | NPC1 (0.51) | NPC1RAB9AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0032670-A1 | Light collector systems and the use of coumarin derivatives as energy converters in such systems | BAYER AG (DE) | 1981-07-29 | — | — | EP | claimed |