SCHEMBL227743

SCHEMBL227743

c1ccc(-c2nc3ccccc3[nH]2)c(-c2nc3ccccc3[nH]2)c1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 10/20 0.78
RAB9A P51151 10/20 0.78
ALDH1A1 P00352 9/20 0.78
KDM4E B2RXH2 9/20 0.78
SMN1; SMN2 Q16637 6/20 0.78
HSD17B10 Q99714 5/20 0.78
NPSR1 Q6W5P4 4/20 0.78
PKM P14618 3/20 0.78
TP53 P04637 3/20 0.78
ABCB11 O95342 1/20 0.78
HPGD P15428 6/20 0.75
GAA P10253 2/20 0.75
MAPT P10636 2/20 0.75
L3MBTL1 Q9Y468 1/20 0.75
GPR55 Q9Y2T6 1/20 0.75
GLA P06280 1/20 0.75
HTT P42858 1/20 0.75
GBA1 P04062 1/20 0.66
CDK1 P06493 1/20 0.66
CDK2 P24941 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29927066 0.90 RAB9A (0.72) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL28415845 0.90 RAB9A (0.72) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL20677815 0.89 NPC1 (0.75) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL30561047 0.88 NPC1 (1.00) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL30634854 0.88 NPC1 (1.00) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL172216 0.88 NPC1 (1.00) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL297468 0.88 RAB9A (0.67) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL19960358 0.87 NPC1 (0.87) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL218892 0.86 NPC1 (1.00) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL3336641 0.86 NPC1 (0.64) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775211-A Method and device for synthesizing phenylene-bisbenzimidazole-tetrasulfonic acid disodium salt 黄冈美丰化工科技有限公司 2025-04-08 CN claimed
CN-119306682-A Synthesis method of phenylene-bisbenzimidazole-tetrasulphonic acid disodium salt 黄冈美丰化工科技有限公司 2025-01-14 CN claimed
US-10099929-B2 Method of producing a graphene material NEOGRAF SOLUTIONS, LLC (US) 2018-10-16 US claimed
CN-106518774-B 2,2 '-(1,2- phenyl) bis- (1H- imidazoles -4,5- dicarboxylic acids), synthetic method and its application 河南中医药大学 2018-09-14 CN claimed
US-20160002046-A1 METHOD OF PRODUCING A GRAPHENE MATERIAL NEOGRAF SOLUTIONS, LLC 2016-01-07 US claimed
WO-2014200649-A1 METHOD OF PRODUCING A GRAPHENE MATERIAL GRAFTECH INTERNATIONAL HOLDINGS INC. (US) 2014-12-18 WO claimed
US-20130240777-A1 HIGHLY THERMAL-CONDUCTIVE POLYIMIDE FILM CONTAINING GRAPHITE POWDER E I DU PONT DE NEMOURS AND COMPANY (US) 2013-09-19 US claimed
EP-2257344-B1 USE OF A GRAPHITIZED SHEET FOR FIRE BARRIER PROTECTION KANEKA CORP (JP) 2012-11-14 EP claimed
WO-2012092505-A1 METAL AND METALLIZED FIBER HYBRID WIRE SYSCOM ADVANCED MATERIALS (US) 2012-07-05 WO claimed
US-8182718-B2 Ligand exchange thermochromic systems and high ε ligands for same PLEOTINT, L.L.C. (US) 2012-05-22 US claimed
US-5766765-A Generally flat member having smooth surfaces and made of highly oriented graphite MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1998-06-16 US claimed
EP-0488356-B1 Processes for producing graphite blocks from graphitizable organic polymers and process for carbonizing graphitizable polymer films MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 1997-03-05 EP claimed
EP-0331375-B1 Optical elements for radiation comprising graphite films MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 1995-08-23 EP claimed
EP-0397152-B1 Process for making a graphite film MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 1994-08-24 EP claimed
EP-0488356-A1 Processes for producing graphite blocks from graphitizable organic polymers and process for carbonizing graphitizable polymer films MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1992-06-03 EP claimed
US-5091025-A Heat treatment of pyropolymer in inert gas MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1992-02-25 US claimed
US-5042059-A Used in optical instruments for x-rays spectroscopes or microscopes, lenses and monochromators MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1991-08-20 US claimed
EP-0408166-A2 Composite polymeric materials GENCORP INC. (US) 1991-01-16 EP claimed
EP-0397152-A1 Process for making a graphite film MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1990-11-14 EP claimed
EP-0331375-A2 Optical elements for radiation comprising graphite films MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1989-09-06 EP claimed