Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11369213 | 0.89 | TBK1 (0.42) | RAB9ANPC1RXFP1TBK1KDM4E | |
| SCHEMBL10823671 | 0.88 | RAB9A (0.58) | RAB9ANPC1RXFP1TBK1GABRA1 | |
| SCHEMBL11366885 | 0.87 | RAB9A (0.49) | RAB9ANPC1RXFP1TBK1GABRA1 | |
| SCHEMBL11357243 | 0.87 | RAB9A (0.49) | RAB9ANPC1RXFP1TBK1GABRA1 | |
| SCHEMBL11361695 | 0.86 | TBK1 (0.60) | RAB9ANPC1RXFP1TBK1GABRA1 | |
| SCHEMBL9204045 | 0.86 | RAB9A (0.65) | RAB9ANPC1RXFP1TBK1KDM4E | |
| SCHEMBL11357935 | 0.86 | RAB9A (0.48) | RAB9ANPC1RXFP1TBK1GABRA1 | |
| SCHEMBL11368720 | 0.84 | RAB9A (0.47) | RAB9ANPC1RXFP1TBK1GABRA1 | |
| SCHEMBL11364824 | 0.82 | RAB9A (0.46) | RAB9ANPC1RXFP1TBK1GABRA1 | |
| SCHEMBL11360715 | 0.80 | RAB9A (0.56) | RAB9ANPC1RXFP1MAOBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4299963-A | ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-11-10 | — | — | US | claimed |
| US-4299963-A | ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-11-10 | — | — | US | disclosed |
| US-4255576-A | 1-Azaxanthone derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-03-10 | — | — | US | disclosed |
| US-4143042-A | ANTIALLERGENS, BRONCHODILATOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-03-06 | — | — | US | disclosed |