SCHEMBL11362437

SCHEMBL11362437

CN(C)C1CCCC1(O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 5/20 0.42
OPRM1 P35372 3/20 0.42
OPRK1 P41145 3/20 0.42
ALDH1A1 P00352 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MEN1 O00255 1/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
OPRD1 P41143 1/20 0.40
KMT2A Q03164 1/20 0.40
TRPA1 O75762 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11362434 1.00 OPRL1 (0.42) OPRL1OPRM1OPRK1ALDH1A1SMN1; SMN2
SCHEMBL11362431 1.00 OPRL1 (0.42) OPRL1OPRM1OPRK1ALDH1A1SMN1; SMN2
Fumaric Acid SCHEMBL11370917 0.90 OPRM1 (0.37) OPRL1OPRM1OPRK1ALDH1A1SMN1; SMN2
Fumaric Acid SCHEMBL11370914 0.90 OPRM1 (0.37) OPRL1OPRM1OPRK1ALDH1A1SMN1; SMN2
Propionic Acid SCHEMBL11370398 0.90 OPRM1 (0.40) OPRL1OPRM1OPRK1ALDH1A1SMN1; SMN2
SCHEMBL11367833 0.84 ALDH1A1 (0.41) OPRL1OPRM1OPRK1ALDH1A1SMN1; SMN2
SCHEMBL11362565 0.83 OPRM1 (0.45) OPRL1OPRM1OPRK1ALDH1A1SMN1; SMN2
SCHEMBL11362567 0.83 OPRM1 (0.45) OPRL1OPRM1OPRK1ALDH1A1SMN1; SMN2
SCHEMBL11362570 0.83 OPRM1 (0.45) OPRL1OPRM1OPRK1ALDH1A1SMN1; SMN2
SCHEMBL11370378 0.82 ALDH1A1 (0.39) OPRL1OPRM1OPRK1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4291059-A 1-PHENYLCYCLOPENTANOL ACYLATE ESTER AND ITS PREPARATION GLAXO GROUP LIMITED (GB) 1981-09-22 US disclosed