Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11366430 | 0.86 | NPC1 (0.53) | LMNASMN1; SMN2ALDH1A1HPGDMIF | |
| SCHEMBL11378055 | 0.86 | APAF1 (0.47) | SMN1; SMN2MIF | |
| SCHEMBL11375518 | 0.86 | MIF (0.42) | MIF | |
| SCHEMBL11372587 | 0.86 | MIF (0.45) | MIF | |
| SCHEMBL11365099 | 0.85 | LMNA (0.44) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11374692 | 0.82 | MIF (0.43) | MIF | |
| SCHEMBL11367968 | 0.82 | MIF (0.60) | SMN1; SMN2MAPTMIF | |
| SCHEMBL11371843 | 0.82 | HTT (0.45) | MIF | |
| SCHEMBL11379586 | 0.80 | MAPT (0.56) | LMNASMN1; SMN2ALDH1A1MAPTMIF | |
| SCHEMBL14183676 | 0.79 | LMNA (0.44) | LMNASMN1; SMN2ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4283403-A | Substituted isoxazolines for control of plant phytopathogens | ELI LILLY AND COMPANY (US) | 1981-08-11 | — | — | US | disclosed |