Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | DHODH | Q02127 | 3/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4424175 | 0.88 | DHODH (0.48) | GAAALDH1A1RAB9ASMN1; SMN2DHODH | |
| SCHEMBL1193764 | 0.82 | CA12 (0.54) | GAAALDH1A1RAB9ASMN1; SMN2DHODH | |
| SCHEMBL4411802 | 0.81 | RAB9A (0.51) | GAAALDH1A1RAB9ASMN1; SMN2DHODH | |
| SCHEMBL4411805 | 0.81 | RAB9A (0.51) | GAAALDH1A1RAB9ASMN1; SMN2DHODH | |
| SCHEMBL12887941 | 0.77 | DHODH (0.46) | GAAALDH1A1RAB9ASMN1; SMN2DHODH | |
| SCHEMBL30730413 | 0.76 | POLB (0.56) | GAAALDH1A1RAB9ASMN1; SMN2DHODH | |
| SCHEMBL1193154 | 0.76 | POLB (0.56) | GAAALDH1A1RAB9ASMN1; SMN2DHODH | |
| SCHEMBL5404742 | 0.75 | MEN1 (0.66) | GAAALDH1A1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL30437351 | 0.75 | RECQL (0.48) | GAAALDH1A1RAB9ASMN1; SMN2TACR1 | |
| SCHEMBL29208258 | 0.75 | TACR1 (0.40) | ALDH1A1RAB9ASMN1; SMN2DHODHTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255587-A | CARBONYLATION OF 2,6-DIALKYLANILINES USING AN OXO-SUBSTITUTED ESTER FOLLOWED BY CATALYTIC HYDROGENATION | BASF AKTIENGESELLSCHAFT (DE) | 1981-03-10 | — | — | US | disclosed |