Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11437311 | 0.86 | FDPS (0.47) | FDPSCA1SMPD1 | |
| SCHEMBL11510893 | 0.85 | CA1 (0.41) | FDPSCA1CYP3A4L3MBTL1CA2 | |
| SCHEMBL9785226 | 0.83 | FDPS (0.40) | FDPSCA1CYP3A4L3MBTL1CA2 | |
| SCHEMBL11497648 | 0.83 | FDPS (0.40) | FDPSCA1CYP3A4L3MBTL1CA2 | |
| SCHEMBL28151694 | 0.76 | TSHR (0.42) | — | |
| SCHEMBL11296124 | 0.74 | — | — | |
| SCHEMBL9463468 | 0.73 | CA1 (0.41) | FDPSCA1CYP3A4CA2ACE2 | |
| SCHEMBL10731785 | 0.72 | FDPS (0.44) | FDPSCA1CYP3A4L3MBTL1CA2 | |
| SCHEMBL3286382 | 0.72 | CA1 (0.52) | FDPSCA1CA2ACE2MAPK1 | |
| SCHEMBL19004774 | 0.72 | CA1 (0.52) | FDPSCA1CA2ACE2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4303670-A | Bicyclic prostaglandins and process for their preparation | FARMITALIA CARLO ERBA (IT) | 1981-12-01 | — | — | US | disclosed |
| US-4277491-A | HYPOTENSIVE, VASODILATORY, ANTI-AGGREGATING, LUTEOLYTIC, CYTOPROTECTIVE | FARMITALIA CARLO ERBA, S.P.A. (IT) | 1981-07-07 | — | — | US | disclosed |
| US-4262016-A | HYPOTENSIVE, VASODILATORY, ANTI-THROMBOTIC | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-04-14 | — | — | US | disclosed |
| US-4254137-A | Bicyclic prostaglandins and process for their preparation | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-03-03 | — | — | US | disclosed |
| US-4230721-A | 2H-CYCLOPENTA/B/FURAN DERIVATIVES | FARMITALIA CARLO ERBA S.P.A. (IT) | 1980-10-28 | — | — | US | disclosed |