SCHEMBL11510893

SCHEMBL11510893

CCCCC(C)C(=O)COP(C)(=O)OC

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.41
FDPS P14324 6/20 0.39
PLA2G2A P14555 2/20 0.37
CA2 P00918 1/20 0.35
SMPD1 P17405 3/20 0.34
ACE2 Q9BYF1 1/20 0.34
CYP3A4 P08684 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ZDHHC7 Q9NXF8 1/20 0.33
LAP3 P28838 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11497648 0.85 FDPS (0.40) CA1FDPSPLA2G2ACA2SMPD1
SCHEMBL9785226 0.85 FDPS (0.40) CA1FDPSPLA2G2ACA2SMPD1
SCHEMBL11364338 0.85 FDPS (0.42) CA1FDPSCA2SMPD1ACE2
SCHEMBL11827440 0.83 MAPT (0.42) CA1FDPSPLA2G2ACA2SMPD1
SCHEMBL11437311 0.81 FDPS (0.47) CA1FDPSSMPD1
SCHEMBL11598685 0.79 PLA2G2A (0.39) CA1FDPSPLA2G2ACA2SMPD1
SCHEMBL11510470 0.78 CA2 (0.44) CA1FDPSPLA2G2ACA2SMPD1
SCHEMBL11510134 0.75 CA2 (0.36) CA1FDPSPLA2G2ACA2CYP3A4
SCHEMBL7020704 0.75 GRIK1 (0.30)
SCHEMBL11315637 0.75 FDPS (0.42) CA1FDPSPLA2G2ACA2SMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4144251-A PROSTAGLANDINS AMERICAN HOME PRODUCTS CORPORATION (US) 1979-03-13 US disclosed
US-4092427-A ANTICOAGULANTS, OXYTOCICS AMERICAN HOME PRODUCTS CORPORATION (US) 1978-05-30 US disclosed
US-4048329-A HYPERTENSIVE AGENTS, BRONCHODILATOR AGENTS, GASTROINTESTINAL DISORDERS, PROSTAGLANDINS AMERICAN HOME PRODUCTS CORPORATION (US) 1977-09-13 US disclosed
US-4048328-A HYPERTENSIVE AGENTS, BRONCHODILATOR AGENTS, GASTROINTESTINAL DISORDERS, PROSTAGLANDINS AMERICAN HOME PRODUCTS CORPORATION (US) 1977-09-13 US disclosed
US-4007171-A PROSTAGLANDIN AMERICAN HOME PRODUCTS CORPORATION (US) 1977-02-08 US disclosed
US-3993686-A Phenyl substituted prostaglandins-C-type analogs THE UPJOHN COMPANY (US) 1976-11-23 US disclosed
US-3987081-A ALKYL DERIVATIVES OF PROSTANOIC ACIDS AND PREPARATION THEREOF AMERICAN HOME PRODUCTS CORPORATION (US) 1976-10-19 US disclosed
US-3959263-A Prostaglandin intermediate AMERICAN HOME PRODUCTS CORPORATION (US) 1976-05-25 US disclosed