4-Nitrobenzoic Acid

4-Nitrobenzoic Acid

SCHEMBL11364446

O=C(O)c1ccc([N+](=O)[O-])cc1.O=C(O)c1ccc([N+](=O)[O-])cc1.OCCOCCO

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.70
SRD5A2 P31213 2/20 0.64
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
CES1 P23141 2/20 0.52
PLA2G4B P0C869 1/20 0.51
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CES2 O00748 1/20 0.50
TSHR P16473 2/20 0.49
MAPK1 P28482 2/20 0.49
GSK3B P49841 1/20 0.49
ALDH1A1 P00352 1/20 0.49
KDM4E B2RXH2 1/20 0.47
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetraethylene Glycol SCHEMBL11369985 0.98 TDP1 (0.68) TDP1SRD5A2MEN1KMT2ACES1
4-Nitrobenzoic Acid SCHEMBL11366971 0.98 TDP1 (0.68) TDP1SRD5A2MEN1KMT2ACES1
4-Nitrobenzoic Acid SCHEMBL11394721 0.88 TDP1 (0.84) TDP1SRD5A2MEN1KMT2ACES1
Terephthalic Acid SCHEMBL28023943 0.84 TDP1 (1.00) TDP1SRD5A2MEN1KMT2ACES1
4-Nitrobenzoic Acid SCHEMBL43476 0.84 TDP1 (1.00) TDP1SRD5A2MEN1KMT2ACES1
Terephthalic Acid SCHEMBL375131 0.84 TSHR (0.57) SRD5A2MEN1KMT2ACES1CA1
Terephthalic Acid SCHEMBL6554172 0.84 TSHR (0.57) SRD5A2MEN1KMT2ACES1CA1
4-Nitrobenzoic Acid SCHEMBL27779244 0.83 TDP1 (0.75) TDP1SRD5A2MEN1KMT2ACES1
SCHEMBL10524262 0.83 KMT2A (0.59) TDP1MEN1KMT2ACES1CA1
4-Nitrobenzoic Acid SCHEMBL27935693 0.82 TDP1 (0.81) TDP1SRD5A2MEN1KMT2ACES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4246392-A Method for the preparation of polyurethane elastomers based on polyethyleneglycol-bis(4-aminobenzoates) IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1981-01-20 US disclosed