Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL6554172 | 1.00 | TSHR (0.57) | TSHRTP53SRD5A2PKMCA1 | |
| Terephthalic Acid SCHEMBL27506116 | 0.98 | TSHR (0.55) | TSHRTP53SRD5A2PKMCA1 | |
| Terephthalic Acid SCHEMBL9165497 | 0.98 | TSHR (0.55) | TSHRTP53SRD5A2PKMCA1 | |
| Terephthalic Acid SCHEMBL674458 | 0.98 | TSHR (0.55) | TSHRTP53SRD5A2PKMCA1 | |
| Tetraethylene Glycol SCHEMBL3841162 | 0.98 | TSHR (0.55) | TSHRTP53SRD5A2PKMCA1 | |
| Terephthalic Acid SCHEMBL10383285 | 0.98 | TSHR (0.55) | TSHRTP53SRD5A2PKMCA1 | |
| Terephthalic Acid SCHEMBL31548541 | 0.96 | TSHR (0.52) | TSHRTP53SRD5A2PKMCA1 | |
| Terephthalic Acid SCHEMBL28153509 | 0.92 | TSHR (0.48) | TSHRTP53SRD5A2PKMCA1 | |
| Paraben SCHEMBL133368 | 0.92 | CA2 (0.64) | TSHRTP53SRD5A2PKMCA1 | |
| Benzoic Acid SCHEMBL818565 | 0.91 | TSHR (0.61) | TSHRTP53SRD5A2PKMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 755 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120192224-A | Recovery type diethylene glycol terephthalate and preparation method thereof | 东丽纤维研究所（中国）有限公司 | 2025-06-24 | — | — | CN | claimed |
| CN-120039498-A | Polyethylene terephthalate heat-resistant plastic logistics tray and preparation process thereof | 江苏兴南复盘物流设备有限公司 | 2025-05-27 | — | — | CN | claimed |
| CN-119490386-A | Method for continuously producing 1, 4-cyclohexanedimethanol by taking waste polyester as raw material | 浙江恒逸石化研究院有限公司 | 2025-02-21 | — | — | CN | claimed |
| CN-118668379-B | High-strength polymer reinforced safety net and preparation method thereof | 山东东锴工程材料有限公司 | 2025-01-24 | — | — | CN | claimed |
| CN-119141997-A | Multilayer polymeric structure and method of making the same | 南亚塑胶工业股份有限公司 | 2024-12-17 | — | — | CN | claimed |
| CN-119083004-A | Preparation method of sweat-releasing and warm-keeping composite fiber blended knitted fabric | 厦门飞隆纺织品有限公司 | 2024-12-06 | — | — | CN | claimed |
| CN-118991197-A | Antibacterial mildew-proof aging-resistant fabric | 杜倍题桥纺织(江苏)有限公司 | 2024-11-22 | — | — | CN | claimed |
| CN-118955280-A | New tail gas absorption process for regenerating waste polyester staple fibers by physical method | 扬州天富龙科技纤维有限公司 | 2024-11-15 | — | — | CN | claimed |
| CN-118878411-A | Novel environment-friendly process for alcoholysis reaction of waste polyester | 富威尔(珠海)复合材料有限公司 | 2024-11-01 | — | — | CN | claimed |
| CN-118852596-A | Chemical regenerated elastic copolyester material, preparation method thereof and filament fiber prepared from chemical regenerated elastic copolyester material | 江苏赛维尔新材料科技有限公司 | 2024-10-29 | — | — | CN | claimed |
| EP-1981930-A1 | METHOD FOR PREPARING PHTHALATE POLYESTER POLYOL-BASED DIMENSIONALLY STABLE SPRAY POLYURETHANE FOAM | STEPAN COMPANY (US) | 2008-10-22 | — | — | EP | claimed |
| WO-2007092060-A1 | METHOD FOR PREPARING PHTHALATE POLYESTER POLYOL-BASED DIMENSIONALLY STABLE SPRAY POLYURETHANE FOAM | STEPAN COMPANY (US) | 2007-08-16 | — | — | WO | claimed |
| WO-2007092005-A1 | METHOD FOR PREPARING PHTHALATE POLYESTER POLYOL-BASED DIMENSIONALLY STABLE SPRAY POLYURETHANE FOAM | STEPAN COMPANY (US) | 2007-08-16 | — | — | WO | claimed |
| US-20070179045-A1 | Mixed catalytic composition | PMC VLISSINGEN NETHERLANDS, B.V. (NL) | 2007-08-02 | — | — | US | claimed |
| US-7241855-B2 | Method for the manufacture of polyesters | ZIMMER AKTIENGESELLSCHAFT (DE) | 2007-07-10 | — | — | US | claimed |
| US-20060175575-A1 | Method for preparing phthalate polyester polyol-based dimensionally stable spray polyurethane foam | BAYER MATERIALSCIENCE LLC | 2006-08-10 | — | — | US | claimed |
| US-20060052575-A1 | Mixed catalyst composition | CHEMTURA ORGANOMETALLICS GMBH (DE) | 2006-03-09 | — | — | US | claimed |
| US-20060047101-A1 | Catalytic composition of organotin compounds | CHEMTURA ORGANOMETALLICS GMBH (DE) | 2006-03-02 | — | — | US | claimed |
| EP-1567473-A1 | MIXED CATALYTIC COMPOSITION | Crompton GmbH (DE) | 2005-08-31 | — | — | EP | claimed |
| WO-2004050597-A1 | MIXED CATALYTIC COMPOSITION | CROMPTON GMBH (DE) | 2004-06-17 | — | — | WO | claimed |