Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.47 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.47 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HRAS | P01112 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8736065 | 0.92 | MAPK1 (0.44) | MAPK1GAARXFP1ALDH1A1CYP3A4 | |
| SCHEMBL11849607 | 0.85 | ALDH1A1 (0.53) | MAPK1GAARXFP1ALDH1A1CYP3A4 | |
| SCHEMBL7716306 | 0.84 | ALDH1A1 (0.46) | MAPK1GAARXFP1ALDH1A1CYP3A4 | |
| Nifluridide SCHEMBL118413 | 0.83 | ALDH1A1 (0.52) | MAPK1GAARXFP1ALDH1A1CYP3A4 | |
| Nifluridide SCHEMBL28173541 | 0.83 | ALDH1A1 (0.52) | MAPK1GAARXFP1ALDH1A1CYP3A4 | |
| SCHEMBL7716273 | 0.81 | MAPK1 (0.49) | MAPK1GAARXFP1ALDH1A1CYP3A4 | |
| SCHEMBL7710558 | 0.80 | ALDH1A1 (0.51) | MAPK1GAARXFP1ALDH1A1CYP3A4 | |
| SCHEMBL8734657 | 0.79 | PDK1 (0.38) | MAPK1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL8734159 | 0.77 | MAPK1 (0.48) | MAPK1GAARXFP1ALDH1A1CYP3A4 | |
| SCHEMBL7713994 | 0.77 | ALDH1A1 (0.48) | MAPK1GAARXFP1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4265901-A | HERBICIDES, INSECTICIDES, PARASITICIDES | ELI LILLY AND COMPANY (US) | 1981-05-05 | — | — | US | disclosed |