Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325813 | 0.85 | PARP10 (0.59) | ALDH1A1PARP10TOP2AKMT2AIRAK4 | |
| SCHEMBL4277719 | 0.82 | MAPK1 (0.59) | ALDH1A1PARP10TOP2AIRAK4MAPK1 | |
| SCHEMBL15521569 | 0.78 | PARP10 (0.51) | PARP10TOP2AKDM4EIRAK4MAPK1 | |
| Propoxur SCHEMBL7591934 | 0.78 | ALDH1A1 (0.88) | ALDH1A1ACHEKDM4EKMT2AL3MBTL1 | |
| SCHEMBL24812339 | 0.77 | MAPK1 (0.62) | ALDH1A1PARP10KMT2AMAPK1PDE4B | |
| Propoxur SCHEMBL6357408 | 0.77 | ALDH1A1 (1.00) | ALDH1A1ACHEKDM4EKMT2AL3MBTL1 | |
| Propoxur SCHEMBL27794 | 0.77 | ALDH1A1 (1.00) | ALDH1A1ACHEKDM4EKMT2AL3MBTL1 | |
| SCHEMBL27775177 | 0.77 | ALDH1A1 (0.65) | ALDH1A1ACHEKDM4EKMT2AL3MBTL1 | |
| SCHEMBL16605596 | 0.75 | PARP10 (0.56) | ALDH1A1PARP10TOP2AKMT2AIRAK4 | |
| SCHEMBL23606802 | 0.75 | PARP10 (0.56) | ALDH1A1PARP10TOP2AKMT2AIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4286020-A | BY SPRAYING A FILM FORMING POLYMER OF POLYVINYL ACETATE, POLYVINYL ETHER OR AN ACRYLIC POLYMER | ENVIRONMENTAL CHEMICALS, INC. (US) | 1981-08-25 | — | — | US | disclosed |