Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.59 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TOP2A | P11388 | 2/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4277719 | 0.93 | MAPK1 (0.59) | PARP10IRAK4MAPK1TOP2APDE4B | |
| SCHEMBL15521569 | 0.92 | PARP10 (0.51) | PARP10IRAK4MAPK1TOP2APDE4B | |
| SCHEMBL24812339 | 0.91 | MAPK1 (0.62) | PARP10MAPK1PDE4BPOLBCYP1A2 | |
| SCHEMBL2411718 | 0.86 | PARP10 (0.56) | PARP10IRAK4MAPK1TOP2APDE4B | |
| SCHEMBL6112896 | 0.86 | PARP10 (0.56) | PARP10IRAK4MAPK1TOP2APOLB | |
| SCHEMBL16605596 | 0.86 | PARP10 (0.56) | PARP10IRAK4MAPK1TOP2APDE4B | |
| SCHEMBL23606802 | 0.86 | PARP10 (0.56) | PARP10IRAK4MAPK1TOP2APDE4B | |
| SCHEMBL30739434 | 0.86 | IRAK4 (0.62) | PARP10IRAK4MAPK1TOP2APDE4B | |
| Acetic Acid Methyl Ester SCHEMBL29204546 | 0.85 | MAPK1 (0.46) | PARP10IRAK4MAPK1TOP2APDE4B | |
| SCHEMBL11364482 | 0.85 | ALDH1A1 (0.61) | PARP10IRAK4MAPK1TOP2APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101166712-B | Hydroxamic acid derivatives and the preparation method thereof | AMOREPACIFIC CORP | 2011-08-03 | — | — | CN | claimed |
| CN-101166712-A | Hydroxamic acid derivatives and the preparation method thereof | AMOREPACIFIC CORP (KR) | 2008-04-23 | — | — | CN | claimed |
| CN-101166712-B | Hydroxamic acid derivatives and the preparation method thereof | AMOREPACIFIC CORP | 2011-08-03 | — | — | CN | disclosed |
| CN-101166712-A | Hydroxamic acid derivatives and the preparation method thereof | AMOREPACIFIC CORP (KR) | 2008-04-23 | — | — | CN | disclosed |
| EP-0852142-A1 | Diamines in the treatment of arrhythmia | SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES (FR) | 1998-07-08 | — | — | EP | disclosed |
| EP-0639973-A1 | DIAMINES IN THE TREATMENT OF ARRHYTHMIA | SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES (FR) | 1995-03-01 | — | — | EP | disclosed |
| WO-1993023024-A1 | DIAMINES IN THE TREATMENT OF ARRHYTHMIA | SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES (FR) | 1993-11-25 | — | — | WO | disclosed |