SCHEMBL11364491

SCHEMBL11364491

CCC(O)C1CCc2ccccc21

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 2/20 0.43
PDPK1 O15530 1/20 0.43
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
DRD2 P14416 1/20 0.42
MAOA P21397 2/20 0.41
MAOB P27338 2/20 0.41
BCHE P06276 1/20 0.41
ADRA2B P18089 1/20 0.41
ADRA2C P18825 1/20 0.41
ACHE P22303 1/20 0.41
ADRA1A P35348 1/20 0.41
HTR6 P50406 1/20 0.41
SIGMAR1 Q99720 4/20 0.40
PRCP P42785 1/20 0.40
IDO1 P14902 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6277434 0.84 HTR1A (0.41) HTR1APDPK1DRD2MAOAMAOB
SCHEMBL19838830 0.80 PDPK1 (0.47) PDPK1MAOAMAOBBCHEADRA2B
SCHEMBL6883953 0.79 HTR2A (0.44) PDPK1DRD2ADRA2BADRA2CADRA1A
SCHEMBL8298173 0.78 PPARA (0.53)
SCHEMBL7678037 0.77 PDPK1 (0.44) PDPK1MAOAMAOBBCHEADRA2B
Methyl Alcohol SCHEMBL14815578 0.77 PRCP (0.49) PDPK1SIGMAR1PRCPIDO1
SCHEMBL9499564 0.77 IDO1 (0.47) PDPK1HTR6IDO1
SCHEMBL3394128 0.76 CARM1 (0.46) PDPK1
SCHEMBL11031060 0.76 PDPK1 (0.43) PDPK1DRD2MAOAMAOBBCHE
SCHEMBL30298334 0.76 PRCP (0.52) PDPK1SIGMAR1PRCPIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4308412-A Indane alkanols and tricyclic isochromans and organoleptic uses thereof INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-12-29 US disclosed
US-4265818-A FOOD FLAVORINGS OR PERFUME COSTNETIC AROMAS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-05-05 US disclosed