Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9076268 | 0.86 | MAPK1 (0.47) | MAPTMAPK1TSHRNPC1RAB9A | |
| SCHEMBL11036050 | 0.80 | TSHR (0.49) | MAPTMAPK1TSHRNPC1RAB9A | |
| SCHEMBL4832512 | 0.79 | MAPK1 (0.56) | MAPK1TSHRNPC1RAB9AALDH1A1 | |
| SCHEMBL7278019 | 0.78 | MAPT (0.39) | PI4KBMAPTMAPK1TSHRNPC1 | |
| SCHEMBL7278026 | 0.78 | MAPT (0.50) | MAPTMAPK1NPC1RAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11411639 | 0.76 | MAPK1 (0.48) | MAPTMAPK1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL9074964 | 0.75 | MAPT (0.42) | MAPTMAPK1TSHRNPC1RAB9A | |
| SCHEMBL3188023 | 0.75 | ATAD2 (0.51) | MAPTMAPK1TSHRNPC1RAB9A | |
| SCHEMBL9075797 | 0.75 | PDE5A (0.37) | MAPTMAPK1TSHRNPC1RAB9A | |
| Lotifazole SCHEMBL286772 | 0.75 | ELOVL1 (0.56) | MAPTMAPK1TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4298606-A | Thiazolylacetamido compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-11-03 | — | — | US | disclosed |