Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 3/20 | 0.51 |
| ▸ | GSK3A | P49840 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13377736 | 0.79 | ABCG2 (0.61) | ABCG2ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL28588654 | 0.79 | ALDH1A1 (0.68) | ABCG2ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL11647789 | 0.78 | PARP1 (0.61) | ALDH1A1HPGDKDM4EMEN1MAPT | |
| SCHEMBL11373879 | 0.78 | MEN1 (0.48) | ALDH1A1HPGDKDM4EMEN1MAPT | |
| SCHEMBL22478923 | 0.78 | CCNB2 (0.52) | ALDH1A1HPGDKDM4EMEN1MAPT | |
| SCHEMBL22478930 | 0.75 | PARP1 (0.53) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL8668538 | 0.74 | ABCG2 (0.62) | ABCG2ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL5442946 | 0.74 | ABCG2 (1.00) | ABCG2ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL30213441 | 0.74 | ABCG2 (1.00) | ABCG2ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL3124589 | 0.73 | ALDH1A1 (0.63) | ABCG2ALDH1A1HPGDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4263304-A | 7 H-indolo[2,3-c]isoquinolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-04-21 | — | — | US | disclosed |