Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.62 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.62 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | GSK3A | P49840 | 2/20 | 0.54 |
| ▸ | GSK3B | P49841 | 2/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.53 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.52 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.52 |
| ▸ | CDK4 | P11802 | 1/20 | 0.52 |
| ▸ | CCND1 | P24385 | 1/20 | 0.52 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666953 | 0.81 | ALDH1A1 (0.50) | ABCG2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL5879238 | 0.81 | PDGFRB (0.62) | ABCG2ROCK2PDGFRBALDH1A1MEN1 | |
| SCHEMBL4703362 | 0.78 | CHEK1 (0.67) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL8667677 | 0.78 | CDK2 (0.50) | ROCK2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL5442946 | 0.77 | ABCG2 (1.00) | ABCG2ROCK2ALDH1A1MEN1KMT2A | |
| SCHEMBL30213441 | 0.77 | ABCG2 (1.00) | ABCG2ROCK2ALDH1A1MEN1KMT2A | |
| SCHEMBL8128623 | 0.77 | ROCK2 (1.00) | ROCK2PDGFRBMEN1KMT2AMAPT | |
| SCHEMBL13377736 | 0.77 | ABCG2 (0.61) | ABCG2ROCK2PDGFRBALDH1A1MEN1 | |
| SCHEMBL21563913 | 0.75 | CDK4 (0.63) | ABCG2ROCK2PDGFRBALDH1A1MEN1 | |
| SCHEMBL21563916 | 0.75 | STING1 (0.53) | ABCG2ROCK2PDGFRBALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649406-B1 | CARBAZOLE DERIVATIVES AND THEIR USE IN COSMETICS, ESPECIALLY FOR MAKE-UP | OREAL (FR) | 1998-12-23 | — | — | EP | claimed |
| US-5543436-A | USED AS PIGMENTS IN COSMETICS, PARTICULARLY INTENDED FOR TREATMENT AND/OR COLORATION OF KERATINOUS SUBSTANCES | L'OREAL (FR) | 1996-08-06 | — | — | US | claimed |
| US-5543436-A | USED AS PIGMENTS IN COSMETICS, PARTICULARLY INTENDED FOR TREATMENT AND/OR COLORATION OF KERATINOUS SUBSTANCES | L'OREAL (FR) | 1996-08-06 | — | — | US | disclosed |