Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | PPM1B | O75688 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25939820 | 0.81 | CA1 (0.44) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL20519996 | 0.81 | CA1 (0.44) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL20519997 | 0.81 | CA1 (0.44) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL763361 | 0.81 | TP53 (0.46) | ALDH1A1MEN1KMT2ATP53CYP3A4 | |
| SCHEMBL10289783 | 0.81 | TP53 (0.46) | ALDH1A1MEN1KMT2ATP53CYP3A4 | |
| SCHEMBL2295020 | 0.81 | TP53 (0.46) | ALDH1A1MEN1KMT2ATP53CYP3A4 | |
| SCHEMBL13616930 | 0.80 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ATP53CYP3A4 | |
| SCHEMBL4617750 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ATP53CYP3A4 | |
| SCHEMBL6900183 | 0.78 | TP53 (0.53) | ALDH1A1MEN1KMT2ATP53CYP3A4 | |
| SCHEMBL13011542 | 0.78 | TP53 (0.53) | ALDH1A1MEN1KMT2ATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4288438-A | Nitrogen-containing heterocyclic ring derivatives and analgesic and anti-inflammatory compositions and methods employing them | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1981-09-08 | — | — | US | disclosed |
| US-4284778-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1981-08-18 | — | — | US | disclosed |
| US-4251533-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1981-02-17 | — | — | US | disclosed |
| US-4186200-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1980-01-29 | — | — | US | disclosed |