Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 5/20 | 0.66 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.66 |
| ▸ | GRK3 | P35626 | 1/20 | 0.65 |
| ▸ | DRD2 | P14416 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | TLR4 | O00206 | 1/20 | 0.64 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.64 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.64 |
| ▸ | MLNR | O43193 | 1/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.64 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | APP | P05067 | 1/20 | 0.64 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16550063 | 0.93 | ADRB2 (0.73) | ADRB2ADRB1GRK3DRD2KDM4E | |
| SCHEMBL11363102 | 0.88 | GRK3 (0.67) | ADRB2ADRB1GRK3DRD2KDM4E | |
| SCHEMBL17950815 | 0.88 | ADRB2 (0.70) | ADRB2ADRB1GRK3DRD2KDM4E | |
| SCHEMBL11357355 | 0.88 | ATM (0.59) | ADRB2ADRB1DRD2KDM4EADRB3 | |
| SCHEMBL11360960 | 0.87 | KDM4E (0.58) | ADRB2ADRB1KDM4EADRB3KMT2A | |
| SCHEMBL11199198 | 0.85 | ADRB2 (0.53) | ADRB2ADRB1GRK3DRD2KDM4E | |
| SCHEMBL16550181 | 0.84 | ADRB2 (0.70) | ADRB2ADRB1GRK3DRD2KDM4E | |
| SCHEMBL17946305 | 0.84 | ADRB2 (0.60) | ADRB2ADRB1SLC22A1ABCB1HTR1A | |
| SCHEMBL11546543 | 0.84 | ADRB2 (0.56) | ADRB2ADRB1GRK3KDM4EADRB3 | |
| SCHEMBL11098798 | 0.83 | ADRB2 (0.51) | ADRB2ADRB1GRK3DRD2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4263325-A | PHENOXY- AMINE DERIVATIVES | AKTIEBOLAGET HASSLE (SE) | 1981-04-21 | — | — | US | disclosed |