Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11364907 | 0.87 | ADRB2 (0.66) | KDM4EADRB2ADRB1ADRB3KMT2A | |
| SCHEMBL11355780 | 0.85 | ATM (0.59) | KDM4EALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL17946305 | 0.84 | ADRB2 (0.60) | ALDH1A1ADRB2ADRB1ADRB3CYP1A2 | |
| SCHEMBL11546543 | 0.84 | ADRB2 (0.56) | KDM4EALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL11357355 | 0.82 | ATM (0.59) | KDM4EALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL10740739 | 0.82 | ADRB2 (0.65) | KDM4EALDH1A1ADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL11084668 | 0.82 | KDM4E (0.53) | KDM4EALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL11279285 | 0.82 | ADRB1 (0.66) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL8055366 | 0.82 | DRD2 (0.67) | KDM4EALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL11360462 | 0.81 | DRD2 (0.56) | KDM4EALDH1A1ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4263325-A | PHENOXY- AMINE DERIVATIVES | AKTIEBOLAGET HASSLE (SE) | 1981-04-21 | — | — | US | disclosed |