SCHEMBL4335919

SCHEMBL4335919

CC(=O)N1CCN(C(C)=O)C1=O

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 11/20 0.39
MAPK1 P28482 1/20 0.39
BRD4 O60885 1/20 0.36
CYP1A2 P05177 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8628607 0.88 BRD4 (0.35) NOTUMMAPK1BRD4CYP2D6CYP2C9
SCHEMBL8271343 0.85 MAPK1 (0.38) NOTUMMAPK1BRD4CYP1A2TDP1
SCHEMBL3123660 0.82 NOTUM (0.39) NOTUMBRD4CYP1A2TDP1CYP2D6
SCHEMBL11416952 0.79 NOTUM (0.37) NOTUMMAPK1BRD4
SCHEMBL14733326 0.79 POLB (0.35) NOTUMMAPK1BRD4POLB
SCHEMBL16472316 0.79 CYP2D6 (0.39) NOTUMMAPK1BRD4CYP2D6CYP2C9
SCHEMBL13292260 0.75 BRD4 (0.37) NOTUMBRD4
SCHEMBL11062290 0.74
SCHEMBL12220734 0.74 NOTUM (0.38) NOTUMBRD4CYP1A2TDP1
SCHEMBL12588975 0.74 NOTUM (0.38) NOTUMBRD4CYP1A2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105400333-A High yellowing-resistant herbaceous refreshing furniture and preparation method thereof SICHUAN LOOK HOUSEHOLD CO LTD 2016-03-16 CN claimed
US-7276463-B2 Polymerization catalyst for α-olefins and process for production of α-olefin polymers therewith JAPAN POLYPROPYLENE CORPORATION (JP) 2007-10-02 US claimed
US-6797745-B1 Hot melt inks containing styrene or terpene polymers XEROX CORPORATION 2004-09-28 US claimed
US-6117223-A Hot melt inks containing polyketones XEROX CORPORATION (US) 2000-09-12 US claimed
US-6106599-A Inks XEROX CORPORATION (US) 2000-08-22 US claimed
US-6103848-A AGENT FOR RENDERING A SUBSTRATE WATER REPELLENT; DENDRITIC MACROMOLECULES INCLUDING DENDRIMERS AND HYPERBRANCHED STRUCTURES; MADE BY POLYMERIZING A DERIVATIZED AMINOFUNCTIONAL ORGANOSILICON COMPOUND DOW CORNING CORPORATION (US) 2000-08-15 US claimed
US-5783169-A RADIOIMMUNOCONJUGATED; DIAGNOSTIC AND THERAPY BROOKHAVEN SCIENCE ASSOCIATES LLC (US) 1998-07-21 US claimed
US-4294973-A Process for the preparation of diacylated 4-imidazolin-2-ones BAYER AKTIENGESELLSCHAFT (DE) 1981-10-13 US claimed
US-4238618-A Process for the preparation of diacylated 4-imidazolin-2-ones BAYER AKTIENGESELLSCHAFT (DE) 1980-12-09 US claimed
US-12108655-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2024-10-01 US disclosed
US-20210399241-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-12-23 US disclosed
CN-113725388-A Organometallic compound and organic light emitting device including the same 三星显示有限公司 2021-11-30 CN disclosed
EP-1902077-B2 NEUTRALISED CATIONIC POLYMER, COMPOSITION CONTAINING SAID POLYMER AND A COSMETIC TREATMENT METHOD OREAL (FR) 2018-07-18 EP disclosed
US-10004923-B2 Neutralised cationic polymer, composition containing said polymer and a cosmetic treatment method L'OREAL (FR) 2018-06-26 US disclosed
EP-0028432-A1 Granular laundry compositions THE PROCTER & GAMBLE COMPANY (US) 1981-05-13 EP disclosed
US-4264466-A LAUNDRY DETERGENTS THE PROCTER & GAMBLE COMPANY (US) 1981-04-28 US disclosed
US-4248928-A TETRAACETYL AKYLENEDIAMINES OR TETRAACETYL GLYCOURIL PEROXY BLEACH PRECURSOR THE PROCTER & GAMBLE COMPANY (US) 1981-02-03 US disclosed
US-4238618-A Process for the preparation of diacylated 4-imidazolin-2-ones BAYER AKTIENGESELLSCHAFT (DE) 1980-12-09 US disclosed
US-4179390-A Laundry additive product THE PROCTER & GAMBLE COMPANY (US) 1979-12-18 US disclosed
US-4130563-A POLYMER INTERMEDIATES BAYER AKTIENGESELLSCHAFT (DE) 1978-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210399241-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME LEF1, CRY1, ODC1 NOTUM 1161/4885MAPK1 2126/4885BRD4 1942/4885
US-12108655-B2 Organometallic compound and organic light-emitting device including the same LEF1, CRY1, ODC1 NOTUM 1161/4885MAPK1 2126/4885BRD4 1942/4885
US-10004923-B2 Neutralised cationic polymer, composition containing said polymer and a cosmetic treatment method KRT18, EYA3, EYA2 NOTUM 92/4885MAPK1 1345/4885BRD4 2344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.