SCHEMBL11366160

SCHEMBL11366160

CN1C(C)(C)CC(CC(=O)CCCCCCCCC(=O)OC2CC(C)(C)N(C)C(C)(C)C2)CC1(C)C

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.42
NAAA Q02083 2/20 0.39
MEN1 O00255 1/20 0.35
GAA P10253 1/20 0.35
KMT2A Q03164 1/20 0.35
EPHX2 P34913 2/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19397279 0.89 SMN1; SMN2 (0.42) SMN1; SMN2NAAAMEN1GAAKMT2A
SCHEMBL28840529 0.89 NAAA (0.47) SMN1; SMN2NAAAMEN1GAAKMT2A
SCHEMBL30744 0.89 NAAA (0.47) SMN1; SMN2NAAAMEN1GAAKMT2A
SCHEMBL21127012 0.89 NAAA (0.47) SMN1; SMN2NAAAMEN1GAAKMT2A
SCHEMBL12244967 0.89 NAAA (0.47) SMN1; SMN2NAAAMEN1GAAKMT2A
SCHEMBL28367479 0.89 NAAA (0.47) SMN1; SMN2NAAAMEN1GAAKMT2A
SCHEMBL13226047 0.89 NAAA (0.47) SMN1; SMN2NAAAMEN1GAAKMT2A
SCHEMBL13508226 0.89 NAAA (0.47) SMN1; SMN2NAAAMEN1GAAKMT2A
SCHEMBL13580302 0.88 SMN1; SMN2 (0.41) SMN1; SMN2NAAAMEN1GAAKMT2A
Ammonia Solution, Strong SCHEMBL5629068 0.87 NAAA (0.46) SMN1; SMN2NAAAMEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2208774-B1 Liquid crystalline medium MERCK PATENT GMBH (DE) 2012-08-29 EP disclosed
EP-2229427-B1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2012-07-18 EP disclosed
EP-2041239-B1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2011-09-07 EP disclosed
EP-2250235-B1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2011-09-07 EP disclosed
EP-2053113-B1 Liquid crystalline medium MERCK PATENT GMBH (DE) 2011-04-13 EP disclosed
EP-1876215-B1 Liquid crystalline medium MERCK PATENT GMBH (DE) 2011-01-12 EP disclosed
EP-1908813-B1 Liquid crystalline medium MERCK PATENT GMBH (DE) 2010-11-03 EP disclosed
WO-2009112146-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2009-09-17 WO disclosed
EP-1563035-B1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2007-09-12 EP disclosed