Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL5629068

CN1C(C)(C)CC(OC(=O)CCCCCCCCC(=O)OC2CC(C)(C)N(C)C(C)(C)C2)CC1(C)C.N

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.45
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.40
KMT2A Q03164 1/20 0.40
EPHX2 P34913 3/20 0.35
TP53 P04637 1/20 0.35
TSHR P16473 2/20 0.34
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28840529 0.98 NAAA (0.47) NAAASMN1; SMN2MEN1GAAKMT2A
SCHEMBL21127012 0.98 NAAA (0.47) NAAASMN1; SMN2MEN1GAAKMT2A
SCHEMBL12244967 0.98 NAAA (0.47) NAAASMN1; SMN2MEN1GAAKMT2A
SCHEMBL30744 0.98 NAAA (0.47) NAAASMN1; SMN2MEN1GAAKMT2A
SCHEMBL13226047 0.98 NAAA (0.47) NAAASMN1; SMN2MEN1GAAKMT2A
SCHEMBL13508226 0.98 NAAA (0.47) NAAASMN1; SMN2MEN1GAAKMT2A
SCHEMBL28367479 0.98 NAAA (0.47) NAAASMN1; SMN2MEN1GAAKMT2A
Water SCHEMBL19542146 0.97 NAAA (0.46) NAAASMN1; SMN2MEN1GAAKMT2A
SCHEMBL463020 0.97 SMN1; SMN2 (0.47) NAAASMN1; SMN2MEN1GAAKMT2A
SCHEMBL223756 0.94 NAAA (0.44) NAAASMN1; SMN2MEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7157586-B2 Bloom-resistant benzotriazole UV absorbers and compositions stabilized therewith CIBA SPECIALTY CHEMCIALS CORPORATION (US) 2007-01-02 US disclosed
EP-1252147-B1 BLOOM-RESISTANT BENZOTRIAZOLE UV ABSORBERS AND COMPOSITIONS STABILIZED THEREWITH CIBA SC HOLDING AG (CH) 2005-08-24 EP disclosed
US-6508847-B2 Discoloration inhibition; stability CIBA SPECIALTY CHEMICALS CORPORATION 2003-01-21 US disclosed
EP-1252147-A1 BLOOM-RESISTANT BENZOTRIAZOLE UV ABSORBERS AND COMPOSITIONS STABILIZED THEREWITH Ciba SC Holding AG (CH) 2002-10-30 EP disclosed
US-20020111404-A1 Bloom-resistant benzotriazole UV absorbers and compositions stabilized therewith WOOD MERVIN (US) 2002-08-15 US disclosed
US-6380285-B1 AS ULTRAVIOLET RADIATION ABSORBERS WHILE NOT BLOOMING WHEN INCORPORATED INTO POLYOLEFIN FILMS CIBA SPECIALTY CHEMICALS CORPORATION 2002-04-30 US disclosed
US-20010023268-A1 Bloom-resistant benzotriazole UV absorbers and compositions stabilized therewith CIBA SPECIALTY CHEMICALS CORP. 2001-09-20 US disclosed
WO-2001056998-A1 BLOOM-RESISTANT BENZOTRIAZOLE UV ABSORBERS AND COMPOSITIONS STABILIZED THEREWITH CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-08-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020111404-A1 Bloom-resistant benzotriazole UV absorbers and compositions stabilized therewith POLL, SCD, RAD51 NAAA 1180/4885SMN1; SMN2 1915/4885MEN1 2456/4885
US-20010023268-A1 Bloom-resistant benzotriazole UV absorbers and compositions stabilized therewith FAAH, DBF4, TPH1 NAAA 1026/4885SMN1; SMN2 2255/4885MEN1 2895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.