Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11296556 | 1.00 | RECQL (0.43) | RECQLLMNAMAPTAPPALDH1A1 | |
| SCHEMBL113525 | 0.71 | RECQL (0.47) | RECQLLMNAMAPTAPPALDH1A1 | |
| SCHEMBL1136763 | 0.71 | RECQL (0.47) | RECQLLMNAMAPTAPPALDH1A1 | |
| SCHEMBL18212657 | 0.71 | RECQL (0.47) | RECQLLMNAMAPTAPPALDH1A1 | |
| SCHEMBL14664249 | 0.71 | RECQL (0.47) | RECQLLMNAMAPTAPPALDH1A1 | |
| SCHEMBL15003320 | 0.68 | RECQL (0.35) | RECQLLMNAMAPTAPPALDH1A1 | |
| SCHEMBL14095057 | 0.68 | MAPT (0.50) | RECQLLMNAMAPTAPPALDH1A1 | |
| SCHEMBL13412686 | 0.68 | MAPT (0.50) | RECQLLMNAMAPTAPPALDH1A1 | |
| SCHEMBL28083524 | 0.67 | KEAP1 (0.32) | ALDH1A1 | |
| SCHEMBL28174069 | 0.67 | ALDH1A1 (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4252976-A | Process for the preparation of thiophenes | BEECHAM GROUP LIMITED (DE) | 1981-02-24 | — | — | US | disclosed |