Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | ATP4A | P20648 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | ATP4B | P51164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11361485 | 0.84 | ACHE (0.87) | ACHELMNAMEN1KMT2ASLC22A1 | |
| SCHEMBL11363099 | 0.80 | ACHE (0.54) | ACHELMNAMEN1KMT2ASLC22A1 | |
| SCHEMBL11362625 | 0.79 | ACHE (0.76) | ACHELMNAMEN1KMT2ASLC22A1 | |
| SCHEMBL11362623 | 0.79 | ACHE (0.76) | ACHELMNAMEN1KMT2ASLC22A1 | |
| SCHEMBL11206540 | 0.78 | ACHE (0.69) | ACHELMNAMEN1KMT2ASLC22A1 | |
| Hydrochloric Acid SCHEMBL11362770 | 0.78 | RAD52 (0.77) | ACHELMNAMEN1KMT2ASLC22A1 | |
| Hydrochloric Acid SCHEMBL11362772 | 0.78 | RAD52 (0.77) | ACHELMNAMEN1KMT2ASLC22A1 | |
| SCHEMBL11377544 | 0.76 | ACHE (0.74) | ACHELMNAMEN1KMT2ASLC22A1 | |
| SCHEMBL11208099 | 0.76 | ACHE (1.00) | ACHELMNAMEN1KMT2ASLC22A1 | |
| SCHEMBL11210012 | 0.76 | ACHE (0.65) | ACHELMNAMEN1KMT2ASLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4279819-A | GASTROINTESTINAL DISORDERS | ALLEN & HANBURYS LTD. (GB) | 1981-07-21 | — | — | US | disclosed |
| US-4255440-A | ANTIALLERGENS, ANTIULCER AGENTS | ALLEN & HANBURYS LIMITED (GB) | 1981-03-10 | — | — | US | disclosed |
| US-4169855-A | ANTIHISTAMINES, ANTISECRETORY AGENTS | Allen & Hansbury, Limited (GB) | 1979-10-02 | — | — | US | disclosed |
| US-4128658-A | HISTAMINE ANTAGONISTS | ALLEN & HANBURYS LIMITED (GB) | 1978-12-05 | — | — | US | disclosed |