Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 1.00 |
| ▸ | CCND1 | P24385 | 4/20 | 1.00 |
| ▸ | HTR2A | P28223 | 1/20 | 0.68 |
| ▸ | HTR2C | P28335 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | DAO | P14920 | 1/20 | 0.57 |
| ▸ | HTR6 | P50406 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29372496 | 0.87 | CDK4 (0.76) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL11624661 | 0.87 | CDK4 (0.76) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL3595410 | 0.87 | CDK4 (0.76) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL1120445 | 0.87 | CDK4 (0.76) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL3347874 | 0.87 | CDK4 (0.76) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL734246 | 0.87 | CDK4 (0.76) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL3134501 | 0.87 | CDK4 (0.76) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL3330892 | 0.87 | CDK4 (0.76) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL17822342 | 0.87 | CDK4 (0.76) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL29379363 | 0.87 | CDK4 (0.76) | CDK4CCND1HTR2AHTR2CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4264753-A | USING AN ORGANO LITHIUM AND DIHETEROCYCLIC BRIDGED AMINE AS CATALYST SYSTEM | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1981-04-28 | — | — | US | disclosed |
| US-4247418-A | ORGANO-LITHIUM COMPOUND WITH A BICYCLIC AMINE | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1981-01-27 | — | — | US | disclosed |