Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.76 |
| ▸ | CCND1 | P24385 | 4/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6258190 | 0.98 | CDK4 (0.73) | CDK4CCND1LMNAHTR2AHTR2C | |
| SCHEMBL135070 | 0.88 | CDK4 (0.78) | CDK4CCND1LMNAHTR2AHTR2C | |
| SCHEMBL11366447 | 0.87 | CDK4 (1.00) | CDK4CCND1LMNAHTR2AHTR2C | |
| SCHEMBL4869090 | 0.86 | CDK4 (0.81) | CDK4CCND1LMNAHTR2AHTR2C | |
| SCHEMBL9703488 | 0.85 | CDK4 (0.82) | CDK4CCND1LMNAHTR2AHTR2C | |
| SCHEMBL5989829 | 0.85 | CDK4 (0.82) | CDK4CCND1LMNAHTR2AHTR2C | |
| Indole SCHEMBL11663600 | 0.84 | CDK4 (0.54) | CDK4CCND1LMNAHTR2AHTR2C | |
| SCHEMBL29379363 | 0.83 | CDK4 (0.76) | CDK4CCND1LMNAHTR2AHTR2C | |
| SCHEMBL17822342 | 0.83 | CDK4 (0.76) | CDK4CCND1LMNAHTR2AHTR2C | |
| SCHEMBL32678603 | 0.83 | CDK4 (0.68) | CDK4CCND1LMNAHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118984868-A | Genetically modified organisms for the production of psychotropic alkaloids | 恩派瑞安神经科学公司 | 2024-11-19 | — | — | CN | claimed |
| US-20230416794-A1 | Engineered Microorganisms for Producing Substituted Tryptamines | ALGAE C INC (CA) | 2023-12-28 | — | — | US | claimed |
| EP-4244333-A1 | ENGINEERED MICROORGANISMS FOR PRODUCING SUBSTITUTED TRYPTAMINES | Algae-C Inc. (CA) | 2023-09-20 | — | — | EP | claimed |
| WO-2022099424-A1 | ENGINEERED MICROORGANISMS FOR PRODUCING SUBSTITUTED TRYPTAMINES | ALGAE-C INC. (CA) | 2022-05-19 | — | — | WO | claimed |
| CN-113321655-A | Preparation and application of evodia rutaecarpa botanical insecticide | 天津农学院 | 2021-08-31 | — | — | CN | claimed |
| CN-111792962-A | Iron fertilizer for improving soil property and preparation and use methods thereof | 江西普瑞丰生态科技有限公司 | 2020-10-20 | — | — | CN | claimed |
| CN-102532218-A | Strictosidine-like alkaloid as well as preparation method and application thereof | UNIV ZHEJIANG | 2012-07-04 | — | — | CN | claimed |
| WO-2000070027-A1 | MATERIALS AND METHODS FOR ENZYMATIC N-ACETYLATION OF ARYLALKYLAMINES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTHA ND HUMAN SERVICES (US) | 2000-11-23 | — | — | WO | claimed |
| WO-2025049640-A1 | MACROLIDE-NOX4 CONJUGATES AND USES THEREOF | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) | 2025-03-06 | — | — | WO | disclosed |
| US-20250017936-A1 | CELL-POTENT BISUBSTRATE INHIBITORS FOR NICOTINAMIDE N-METHYLTRANSFERASE (NNMT) AND USES THEREOF | PURDUE RESEARCH FOUNDATION | 2025-01-16 | — | — | US | disclosed |
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | disclosed |
| CN-118984868-A | Genetically modified organisms for the production of psychotropic alkaloids | 恩派瑞安神经科学公司 | 2024-11-19 | — | — | CN | disclosed |
| EP-4436566-A1 | CELL-POTENT BISUBSTRATE INHIBITORS FOR NICOTINAMIDE N-METHYLTRANSFERASE (NNMT) AND USES THEREOF | Purdue Research Foundation (US) | 2024-10-02 | — | — | EP | disclosed |
| CN-117486777-A | Indoloethylamine derivative and preparation method and application thereof | 浙江中医药大学 | 2024-02-02 | — | — | CN | disclosed |
| US-5750724-A | SEROTONIN 5-HT REUPTAKE INHIBITORS; ANTIDEPRESSANTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |
| WO-1997017343-A1 | INDOLEALKYL DERIVATIVES OF BENZODIOXANMETHYLAMINE AS 5-HT1A RECEPTOR LIGANDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |
| EP-0240352-A2 | 5-Fluorouracil derivatives and processes for producing thereof | Chisso Corporation (JP) | 1987-10-07 | — | — | EP | disclosed |
| US-4210590-A | WITH BORANE COMPLEX REAGENT IN PRESENCE OF TRIFLUOROACETIC ACID | MCNEIL LABORATORIES, INCORPORATED (US) | 1980-07-01 | — | — | US | disclosed |
| US-4076530-A | Dry photographic copying method for producing Te images | FUJI PHOTO FILM CO., LTD. (JA) | 1978-02-28 | — | — | US | disclosed |
| US-4062685-A | ORGANO-TELLURIUM COMPOUND | FUJI PHOTO FILM CO., LTD. (JA) | 1977-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250017936-A1 | CELL-POTENT BISUBSTRATE INHIBITORS FOR NICOTINAMIDE N-METHYLTRANSFERASE (NNMT) AND USES THEREOF | NNMT, NAMPT, NNT | CDK4 1851/4885CCND1 2978/4885LMNA 4161/4885 |
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | BCAT1, BCAT2, PELP1 | CDK4 2187/4885CCND1 2556/4885LMNA 4108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.