Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.76 |
| ▸ | CCND1 | P24385 | 4/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30063707 | 1.00 | CDK4 (0.76) | CDK4CCND1LMNAHTR2AHTR2C | |
| Alcohol SCHEMBL734139 | 0.94 | CDK4 (0.68) | CDK4CCND1LMNAHTR2AHTR2C | |
| SCHEMBL30701168 | 0.88 | CDK4 (0.78) | CDK4CCND1LMNAHTR2AHTR2C | |
| SCHEMBL4992403 | 0.88 | CDK4 (0.78) | CDK4CCND1LMNAHTR2AHTR2C | |
| SCHEMBL11366447 | 0.87 | CDK4 (1.00) | CDK4CCND1LMNAHTR2AHTR2C | |
| SCHEMBL24398975 | 0.85 | CDK4 (0.82) | CDK4CCND1LMNAHTR2AHTR2C | |
| SCHEMBL1293253 | 0.85 | CDK4 (0.82) | CDK4CCND1LMNAHTR2AHTR2C | |
| SCHEMBL29368287 | 0.85 | CDK4 (0.82) | CDK4CCND1LMNAHTR2AHTR2C | |
| SCHEMBL2076869 | 0.83 | CDK4 (0.68) | CDK4CCND1LMNAHTR2AHTR2C | |
| SCHEMBL30342074 | 0.83 | CDK4 (0.68) | CDK4CCND1LMNAHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110776497-B | Preparation method for constructing two-dimensional organic layer based on cation-pi interaction | 西北工业大学 | 2022-12-13 | — | — | CN | claimed |
| CN-110776497-A | Preparation method for constructing two-dimensional organic layer based on cation-pi interaction | 西北工业大学 | 2020-02-11 | — | — | CN | claimed |
| CN-101824027-B | Polysubstituted tetrahydroquinoline derivative with optical activity and synthetic method and use thereof | UNIV BEIJING | 2013-09-04 | — | — | CN | claimed |
| EP-2317849-A1 | METHOD FOR TREATING PULMONARY DISEASES USING RHO KINASE INHIBITOR COMPOUNDS | Inspire Pharmaceuticals, Inc. (US) | 2011-05-11 | — | — | EP | claimed |
| CN-101824027-A | Polysubstituted tetrahydroquinoline derivative with optical activity and synthetic method and use thereof | UNIV BEIJING | 2010-09-08 | — | — | CN | claimed |
| JP-2110107-A | — | — | None | — | — | JP | disclosed |
| CN-117024759-A | Organic Pt metal macrocyclic group two-dimensional supermolecule assembly constructed based on oriented cation-pi action, and preparation method and application thereof | 陕西中医药大学 | 2023-11-10 | — | — | CN | disclosed |
| WO-2023141595-A2 | FUNCTIONALIZED ALKYLAMINES | TERRAN BIOSCIENCES, INC. (US) | 2023-07-27 | — | — | WO | disclosed |
| EP-3298003-B1 | BENZOIMIDAZOLE DERIVATIVES AS PAD4 INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2023-04-19 | — | — | EP | disclosed |
| EP-3298003-B1 | BENZOIMIDAZOLE DERIVATIVES AS PAD4 INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2023-04-19 | — | — | EP | disclosed |
| CN-110776497-B | Preparation method for constructing two-dimensional organic layer based on cation-pi interaction | 西北工业大学 | 2022-12-13 | — | — | CN | disclosed |
| EP-3472162-B1 | HETEROARYL ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | HOFFMANN LA ROCHE (CH) | 2021-11-17 | — | — | EP | disclosed |
| EP-0061333-B1 | 9-(2-(3-INDOLYL)ETHYL)-1-OXA-4,9-DIAZASPIRO(5.5)UNDECAN-3-ONES | SYNTEX (U.S.A.) INC. (US) | 1986-01-02 | — | — | EP | disclosed |
| EP-0022634-B1 | ACYLATED INDOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS AND DRUGS COMPRISING THEM | TEIJIN LIMITED (JP) | 1983-04-06 | — | — | EP | disclosed |
| EP-0061333-A1 | 9-(2-(3-Indolyl)ethyl)-1-oxa-4,9-diazaspiro(5.5)undecan-3-ones | SYNTEX (U.S.A.) INC. (US) | 1982-09-29 | — | — | EP | disclosed |
| US-4332804-A | TREATMENT OF HYPERTENSION, CONGESTIVE HEART FAILURE, ARRHYTHMIA, MIGRAINE, VASOSPASTIC DISORDERS AND ASTHMA | SYNTEX (U.S.A.) INC. (US) | 1982-06-01 | — | — | US | disclosed |
| EP-0022634-A1 | Acylated indole derivatives, processes for their preparation and pharmaceutical compositions and drugs comprising them | TEIJIN LIMITED (JP) | 1981-01-21 | — | — | EP | disclosed |
| US-4066763-A | Thiazinoindoles useful as antidepressants | AYERST MCKENNA AND HARRISON LTD. (CA) | 1978-01-03 | — | — | US | disclosed |
| US-4012511-A | ANTIULCER AGENTS | AYERST MCKENNA & HARRISON LTD. (CA) | 1977-03-15 | — | — | US | disclosed |
| US-3962236-A | ANTIDEPRESSANTS, ANTI-ULCER | AYERST MCKENNA AND HARRISON LTD. (CA) | 1976-06-08 | — | — | US | disclosed |