SCHEMBL11366605

SCHEMBL11366605

CC(C)C(=O)OCC(C)(C)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.40
ALDH1A1 P00352 2/20 0.37
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.37
ACACB O00763 1/20 0.35
ACACA Q13085 1/20 0.35
DGAT1 O75907 5/20 0.33
ACLY P53396 1/20 0.32
HTT P42858 1/20 0.32
TSHR P16473 2/20 0.32
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2B Q13224 1/20 0.32
GRIN2C Q14957 1/20 0.32
GRIN3A Q8TCU5 1/20 0.32
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21611809 0.83 GRIN2D (0.47) CYP2C9ALDH1A1MAPTACACBACACA
SCHEMBL7933222 0.82 ALDH1A1 (0.37) ALDH1A1POLBMAPTHTTGRIN2D
SCHEMBL11216426 0.82 ALDH1A1 (0.37) ALDH1A1POLBMAPTHTTGRIN2D
SCHEMBL11633361 0.80 PRSS1 (0.36) ALDH1A1POLBMAPTHTTGRIN2D
SCHEMBL12413765 0.78 ALDH1A1 (0.35) ALDH1A1POLBMAPTDGAT1HTT
SCHEMBL882160 0.78 ALDH1A1 (0.40) ALDH1A1POLBMAPTHTTTSHR
SCHEMBL7934757 0.78 ALDH1A1 (0.40) ALDH1A1POLBMAPTHTTTSHR
SCHEMBL12522829 0.77 ALDH1A1 (0.34) ALDH1A1POLBMAPTHTT
Dimebutic Acid SCHEMBL29589488 0.77 MMP8 (0.36) CYP2C9ALDH1A1ACACBACACAHTT
SCHEMBL20225712 0.77 CYP2C9 (0.33) CYP2C9ACACBACACADGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4273934-A REACTING ISOBUTYRALDEHYDE WITH AN ALKALINE EARTH METAL HYDROXIDE AND A CARBOXYLIC ACID OR CORRESPONDING METAL SALT BASF AKTIENGESELLSCHAFT (DE) 1981-06-16 US disclosed
US-4092270-A MINERAL ACID-TREATED TANTALUM, TITANIUM, NIOBIUM OR ZIRCONIUM OXIDE-SILICA GEL COMPLEX EASTMAN KODAK COMPANY (US) 1978-05-30 US disclosed
US-4035389-A ISOANHYDRIDES, FORMALDEHYDE EASTMAN KODAK COMPANY (US) 1977-07-12 US disclosed
US-4024080-A Production of 2,2-disubstituted propiolactones EASTMAN KODAK COMPANY (US) 1977-05-17 US disclosed
US-3931237-A Production of 2,2-disubstituted propiolactones EASTMAN KODAK COMPANY (US) 1976-01-06 US disclosed