Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | GMNN | O75496 | 1/20 | 0.63 |
| ▸ | TTR | P02766 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.63 |
| ▸ | DHODH | Q02127 | 1/20 | 0.63 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8689929 | 0.86 | LMNA (0.69) | LMNACYP1A2CYP2C9CYP3A4MEN1 | |
| SCHEMBL25392363 | 0.84 | LMNA (0.76) | LMNACYP1A2CYP2C9CYP3A4MEN1 | |
| SCHEMBL13299182 | 0.84 | LMNA (0.65) | LMNACYP1A2CYP2C9CYP3A4MEN1 | |
| SCHEMBL11521452 | 0.83 | LMNA (0.67) | LMNACYP1A2CYP2C9CYP3A4MEN1 | |
| SCHEMBL3807352 | 0.80 | PDE4D (0.64) | LMNACYP1A2CYP2C9CYP3A4MEN1 | |
| SCHEMBL11579364 | 0.80 | PDE4D (0.63) | LMNACYP1A2CYP2C9CYP3A4MEN1 | |
| SCHEMBL12608890 | 0.79 | LMNA (0.79) | LMNACYP1A2CYP2C9CYP3A4MEN1 | |
| SCHEMBL13653030 | 0.79 | LMNA (0.74) | LMNACYP1A2CYP2C9CYP3A4MEN1 | |
| Acetic Acid SCHEMBL28343561 | 0.78 | PDE4D (0.61) | LMNACYP1A2CYP2C9CYP3A4MEN1 | |
| Niflumic Acid SCHEMBL24706 | 0.78 | DHODH (1.00) | LMNACYP1A2CYP2C9CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273777-A | PYRIDINE-3-CARBOXYLIC ACID ESTERS | LABORATORIOS BAGO S.A. (AR) | 1981-06-16 | — | — | US | claimed |
| US-4273777-A | PYRIDINE-3-CARBOXYLIC ACID ESTERS | LABORATORIOS BAGO S.A. (AR) | 1981-06-16 | — | — | US | disclosed |