Niflumic Acid

Niflumic Acid

SCHEMBL24706

O=C(O)c1cccnc1Nc1cccc(C(F)(F)F)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 6/20 1.00
LMNA P02545 5/20 1.00
MEN1 O00255 5/20 1.00
KMT2A Q03164 5/20 1.00
PKM P14618 2/20 1.00
ALDH1A1 P00352 2/20 1.00
GMNN O75496 1/20 1.00
TTR P02766 1/20 1.00
CYP1A2 P05177 1/20 1.00
CYP3A4 P08684 1/20 1.00
CYP2C9 P11712 1/20 1.00
NFKB1 P19838 1/20 1.00
UGT1A1 P22309 1/20 1.00
PTGS1 P23219 1/20 1.00
PTGS2 P35354 1/20 1.00
PMP22 Q01453 1/20 1.00
TEAD4 Q15561 1/20 1.00
HIF1A Q16665 1/20 1.00
GPR35 Q9HC97 1/20 1.00
TDP1 Q9NUW8 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Niflumic Acid SCHEMBL29364001 1.00 DHODH (1.00) DHODHLMNAMEN1KMT2APKM
Niflumic Acid SCHEMBL29373503 1.00 DHODH (1.00) DHODHLMNAMEN1KMT2APKM
Niflumic Acid SCHEMBL4886924 1.00 DHODH (1.00) DHODHLMNAMEN1KMT2APKM
Niflumic Acid SCHEMBL8925125 0.99 DHODH (0.97) DHODHLMNAMEN1KMT2APKM
Niflumic Acid SCHEMBL10435526 0.99 LMNA (0.97) DHODHLMNAMEN1KMT2APKM
Niflumic Acid SCHEMBL5251418 0.92 LMNA (0.84) DHODHLMNAMEN1KMT2APKM
Niflumic Acid SCHEMBL5305825 0.90 LMNA (0.81) DHODHLMNAMEN1KMT2APKM
SCHEMBL12608890 0.88 LMNA (0.79) DHODHLMNAMEN1KMT2APKM
SCHEMBL4204237 0.88 LMNA (0.79) DHODHLMNAMEN1KMT2APKM
SCHEMBL22492824 0.88 LMNA (0.78) DHODHLMNAMEN1KMT2APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 16289 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4744663-A2 SKIN COMPOSITION Eaderm Co., Ltd. (JP) 2026-05-20 EP claimed
CN-122037217-A Silver-based catalyst and preparation method and application thereof 山东明化新材料有限公司 2026-05-15 CN claimed
EP-4741492-A2 NECROSIS INHIBITOR Linkgevity Limited (GB) 2026-05-13 EP claimed
CN-122010832-A Method for preparing niflumic acid crystal form by melt crystallization 沈阳化工大学 2026-05-12 CN claimed
EP-4683527-A1 VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF Ready Mix Naturals, LLC (US) 2026-01-28 EP claimed
US-12497381-B2 Vaporizable alkaloid compositions and methods of use thereof Ready Mix Naturals, LLC (US) 2025-12-16 US claimed
US-12478091-B2 Vaporizable alkaloid compositions and methods of use thereof Ready Mix Naturals, LLC (US) 2025-11-25 US claimed
EP-4648769-A2 NECROSIS INHIBITOR Linkgevity Limited (GB) 2025-11-19 EP claimed
US-20250325571-A1 TREATMENT OF BINGE EATING DISORDER USING PSYCHEDELICS TRYP THERAPEUTICS INC (CA) 2025-10-23 US claimed
US-20250312336-A1 Compositions And Methods For Treating Cancer With Calcium Channel Inhibitors INSTITUTE FOR CANCER RES D/B/A THE RES INSTITUTE OF FOX CHASE CANCER CENTER (US) 2025-10-09 US claimed
EP-0114886-A1 IMPROVED ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING CAFFEINE. SUNSHINE ABRAHAM (US) 1984-08-08 EP claimed
US-4455146-A THERMOPLASTIC ELASTOMERS, OILS OR FATTY ACID, TACKFIER, AND A MEDICINE HISAMITSU PHARMACEUTICAL CO., LTD. (JP) 1984-06-19 US claimed
WO-1984000490-A1 IMPROVED ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING CAFFEINE AND METHODS OF USING SAME SUNSHINE ABRAHAM 1984-02-16 WO claimed
US-4344929-A Method of delivering drug with aid of effervescent activity generated in environment of use ALZA CORPORATION (US) 1982-08-17 US claimed
EP-0016460-B1 SALICYLAMIDE ESTERS HAVING THERAPEUTICAL ACTIVITY, PROCESS FOR THEIR PREPARATION AND RELATED PHARMACEUTICAL COMPOSITION NEOPHARMED S.p.A. (IT) 1982-07-28 EP claimed
EP-0051278-A1 Soft tertiary amine esters of bio-affecting carboxylic acids, processes for preparing and a pharmaceutical composition containing the same MERCK & CO. INC. (US) 1982-05-12 EP claimed
EP-0040899-A2 Method of delivering drug with aid of effervescent activity generated in environment of use ALZA CORPORATION (US) 1981-12-02 EP claimed
US-4268685-A Salicylamide esters and related pharmaceutical composition NEOPHARMED S.P.A. (IT) 1981-05-19 US claimed
EP-0016460-A1 Salicylamide esters having therapeutical activity, process for their preparation and related pharmaceutical composition NEOPHARMED S.p.A. (IT) 1980-10-01 EP claimed
US-4160828-A ANTIINFLAMMATORY AND ANTIRHEUMATIC HOECHST AKTIENGESELLSCHAFT (DE) 1979-07-10 US claimed