Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 10/20 | 0.44 |
| ▸ | BCHE | P06276 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11371968 | 0.89 | ACHE (0.60) | ACHEBCHE | |
| SCHEMBL11362161 | 0.84 | TDP1 (0.52) | ACHEBCHEMAOB | |
| SCHEMBL11370553 | 0.83 | TDP1 (0.55) | ACHEBCHEMAOB | |
| SCHEMBL11372202 | 0.81 | ACHE (0.66) | ACHEBCHE | |
| SCHEMBL11013833 | 0.81 | ACHE (0.62) | ACHEBCHE | |
| SCHEMBL10179103 | 0.78 | ALDH1A1 (0.51) | ACHEBCHESMN1; SMN2MAOB | |
| SCHEMBL11364365 | 0.75 | ALDH1A1 (0.52) | NPC1CASP3RAB9ASMN1; SMN2SENP8 | |
| SCHEMBL11209483 | 0.72 | NPC1 (0.48) | NPC1CASP3RAB9ASMN1; SMN2SENP8 | |
| SCHEMBL10729240 | 0.71 | ACHE (0.49) | ACHEBCHE | |
| SCHEMBL11071100 | 0.70 | NPC1 (0.45) | NPC1CASP3RAB9ASMN1; SMN2SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4279819-A | GASTROINTESTINAL DISORDERS | ALLEN & HANBURYS LTD. (GB) | 1981-07-21 | — | — | US | disclosed |
| US-4255440-A | ANTIALLERGENS, ANTIULCER AGENTS | ALLEN & HANBURYS LIMITED (GB) | 1981-03-10 | — | — | US | disclosed |
| US-4203909-A | ANTIULCER | BRISTOL-MYERS COMPANY (US) | 1980-05-20 | — | — | US | disclosed |
| US-4169855-A | ANTIHISTAMINES, ANTISECRETORY AGENTS | Allen & Hansbury, Limited (GB) | 1979-10-02 | — | — | US | disclosed |
| US-4128658-A | HISTAMINE ANTAGONISTS | ALLEN & HANBURYS LIMITED (GB) | 1978-12-05 | — | — | US | disclosed |