⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29653537 | 1.00 | — | — | |
| Bromide SCHEMBL31024397 | 0.97 | — | — | |
| Bromide SCHEMBL18228015 | 0.97 | — | — | |
| Cyanide SCHEMBL27870989 | 0.93 | ALDH1A1 (0.37) | — | |
| Formaldehyde SCHEMBL29031592 | 0.93 | P2RX7 (0.40) | — | |
| SCHEMBL29067869 | 0.87 | TRIM24 (0.42) | — | |
| Dimethylformamide SCHEMBL27472098 | 0.84 | TRIM24 (0.40) | — | |
| Formic Acid Methyl Ester SCHEMBL29281000 | 0.84 | TRIM24 (0.40) | — | |
| SCHEMBL31016865 | 0.83 | — | — | |
| Ethoxycarbonyl Group SCHEMBL27868253 | 0.78 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380738-A | Synthetic method of 3-bromo-4-chloro-2-methylpyridine | 都创(重庆)医药科技有限公司 | 2022-04-22 | — | — | CN | claimed |
| CN-103896834-B | 2-Cyano-3-cyclobutylpyridine and chemical synthesis method thereof | 南通大学 | 2017-02-15 | — | — | CN | claimed |
| CN-105198802-A | Preparation method of 2-methyl-3-bromopyridine | JIANGSU MENGDE PLATING CHEMICALS CO LTD | 2015-12-30 | — | — | CN | claimed |
| CN-104945313-A | Preparation method of 2-methyl-3-bromopyridine | HONG SHUAIJIN | 2015-09-30 | — | — | CN | claimed |
| EP-2350090-B1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC (CA) | 2015-06-03 | — | — | EP | claimed |
| CN-104069737-A | Recycling and purifying method of ammonia-containing industrial waste gas | CHENGDU ORGANIC CHEMICALS CO | 2014-10-01 | — | — | CN | claimed |
| CN-103896834-A | 2-Cyano-3-cyclobutylpyridine and chemical synthesis method thereof | UNIV NANTONG | 2014-07-02 | — | — | CN | claimed |
| US-8263606-B2 | Spiro-oxindole compounds and their use as therapeutic agents | XENON PHARMACEUTICALS INC. (CA) | 2012-09-11 | — | — | US | claimed |
| US-20110306662-A1 | Steroid-Derived Cyclopamine Analogs and Methods for Using the Same in the Prevention or Treatment of Cancer | The Wistar Institute and The Trustees of the University of Pennsylvania (US) | 2011-12-15 | — | — | US | claimed |
| EP-2350090-A2 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | Xenon Pharmaceuticals Inc. (CA) | 2011-08-03 | — | — | EP | claimed |
| US-20100298281-A1 | Steroid-Derived Cyclopamine Analogs and Methods for Using the Same in the Prevention or Treatment of Cancer | THE WISTAR INSTITUTE (US) | 2010-11-25 | — | — | US | claimed |
| US-20100249402-A1 | NOVEL BENZAMIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OSTEPOROSIS COMPRISING THE SAME | DONG WHA PHARMACEUTICAL CO. LTD. (KR) | 2010-09-30 | — | — | US | claimed |
| US-20100137299-A1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2010-06-03 | — | — | US | claimed |
| WO-2010045251-A2 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS, INC. (CA) | 2010-04-22 | — | — | WO | claimed |
| EP-2170878-A1 | NOVEL BENZAMIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OSTEOPOROSIS COMPRISING THE SAME | Dong Wha Pharmaceutical Co., Ltd. (KR) | 2010-04-07 | — | — | EP | claimed |
| WO-2009058945-A1 | STEROID-DERIVED CYCLOPAMINE ANALOGS AND METHODS FOR USING THE SAME IN THE PREVENTION OR TREATMENT OF CANCER | THE WISTAR INSTITUTE (US) | 2009-05-07 | — | — | WO | claimed |
| WO-2009017346-A1 | NOVEL BENZAMIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OSTEOPOROSIS COMPRISING THE SAME | DONG WHA PHARMACEUTICAL CO., LTD. (KR) | 2009-02-05 | — | — | WO | claimed |
| CN-100427468-C | Apparatus and method for separating 5-bromo-2-methyl pyridine isomer by intermittent rectification under vacuum | UNIV TIANJIN (CN) | 2008-10-22 | — | — | CN | claimed |
| CN-1850803-A | Apparatus and method for separating 5-bromo-2-methyl pyridine isomer by intermittent rectification under vacuum | UNIV TIANJIN (CN) | 2006-10-25 | — | — | CN | claimed |
| CN-1604776-A | 4-4-alkoxy-3-hydroxyphenyl-2-pyrrolidone derivatives as pde-4 inhibitors for the treatment of neurological syndromes | MEMORY PHARM CORP (US) | 2005-04-06 | — | — | CN | claimed |