SCHEMBL11367285

SCHEMBL11367285

Nc1ccccc1S(=O)(=O)Nc1nccnc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC40A1 Q9NP59 3/20 0.50
NFKBIA P25963 2/20 0.50
RELA Q04206 2/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CCR4 P51679 2/20 0.45
USP2 O75604 1/20 0.45
LMNA P02545 1/20 0.45
RXFP1 Q9HBX9 2/20 0.43
ALDH1A1 P00352 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CA9 Q16790 2/20 0.43
GAA P10253 1/20 0.42
PTGDR2 Q9Y5Y4 4/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CYP2C9 P11712 1/20 0.41
CA4 P22748 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2447502 0.84 PTGDR2 (0.54) SLC40A1CCR4RXFP1ALDH1A1L3MBTL1
SCHEMBL1731259 0.79 CCR4 (0.69) SLC40A1CCR4
SCHEMBL2449417 0.78 RXFP1 (0.66) SLC40A1RXFP1PTGDR2CYP2C9
SCHEMBL10791703 0.78 CCR4 (0.64) SLC40A1NFKBIARELAMEN1KMT2A
SCHEMBL27564952 0.76 CCR4 (0.49) SLC40A1NFKBIARELAMEN1KMT2A
SCHEMBL3837982 0.76 NFKBIA (0.60) SLC40A1NFKBIARELAMEN1KMT2A
SCHEMBL11364110 0.75 SLC40A1 (0.58) SLC40A1CCR4LMNARXFP1ALDH1A1
SCHEMBL11367281 0.75 KMT2A (0.62) MEN1KMT2ATDP1LMNAALDH1A1
SCHEMBL10888517 0.74 NFKBIA (0.58) SLC40A1NFKBIARELAMEN1KMT2A
SCHEMBL2762847 0.73 SMN1; SMN2 (0.62) SLC40A1NFKBIARELAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4299962-A Process for synthesizing 2-sulphanilamido-3-methoxypyrazine PIERREL S.P.A. (IT) 1981-11-10 US claimed
US-4299962-A Process for synthesizing 2-sulphanilamido-3-methoxypyrazine PIERREL S.P.A. (IT) 1981-11-10 US disclosed