Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | AURKA | O14965 | 1/20 | 0.57 |
| ▸ | DHFR | P00374 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | EDNRA | P25101 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6747752 | 0.87 | TSHR (0.63) | KMT2AMEN1LMNATSHRSMN1; SMN2 | |
| SCHEMBL6038507 | 0.84 | KMT2A (0.52) | KMT2AMEN1LMNATSHRSMN1; SMN2 | |
| SCHEMBL11358288 | 0.78 | MEN1 (0.40) | KMT2AMEN1LMNATSHRAURKA | |
| Sulfalene SCHEMBL28404 | 0.77 | MEN1 (1.00) | KMT2AMEN1LMNATSHRAURKA | |
| Sulfalene SCHEMBL1893333 | 0.77 | MEN1 (1.00) | KMT2AMEN1LMNATSHRAURKA | |
| Sulfalene SCHEMBL3964512 | 0.76 | MEN1 (0.90) | KMT2AMEN1LMNATSHRAURKA | |
| SCHEMBL11367285 | 0.75 | SLC40A1 (0.50) | KMT2AMEN1LMNATSHRCYP2C9 | |
| Sulfadiazine SCHEMBL1486826 | 0.75 | LMNA (0.96) | KMT2AMEN1LMNATSHRAURKA | |
| Sulfadiazine SCHEMBL11611850 | 0.75 | LMNA (0.96) | KMT2AMEN1LMNATSHRAURKA | |
| Sulfadiazine SCHEMBL1486830 | 0.75 | LMNA (0.96) | KMT2AMEN1LMNATSHRAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4299962-A | Process for synthesizing 2-sulphanilamido-3-methoxypyrazine | PIERREL S.P.A. (IT) | 1981-11-10 | — | — | US | claimed |
| US-4299962-A | Process for synthesizing 2-sulphanilamido-3-methoxypyrazine | PIERREL S.P.A. (IT) | 1981-11-10 | — | — | US | disclosed |