SCHEMBL11367384

SCHEMBL11367384

CCCCNC(=O)c1nc(Br)c(Br)[nH]1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.43
DRD3 P35462 1/20 0.43
TSHR P16473 2/20 0.42
HTT P42858 2/20 0.42
GPR84 Q9NQS5 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KDM4E B2RXH2 4/20 0.40
ALDH1A1 P00352 2/20 0.40
ALOX15 P16050 1/20 0.40
RAB9A P51151 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA3 P07451 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA13 Q8N1Q1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL164028 0.72 TSHR (0.46) DRD2DRD3TSHRHTTGPR84
SCHEMBL8594130 0.71 HDAC3 (0.60) DRD2DRD3TSHRHTTSMN1; SMN2
SCHEMBL2352832 0.70 TSHR (0.55) DRD2DRD3TSHRHTTSMN1; SMN2
SCHEMBL161198 0.69 TSHR (0.46) DRD2DRD3TSHRHTTGPR84
SCHEMBL11168750 0.68 ALOX15 (0.47) TSHRALOX15RAB9AMMP2
Carbamic Acid SCHEMBL11235370 0.67 HDAC3 (0.55) DRD2DRD3TSHRHTTSMN1; SMN2
SCHEMBL28378029 0.67 HDAC3 (0.58) DRD2DRD3HTTSMN1; SMN2KDM4E
SCHEMBL11260129 0.67 HTT (0.47) DRD2DRD3TSHRHTTGPR84
SCHEMBL28378370 0.66 DAGLA (0.58) DRD2DRD3SMN1; SMN2KDM4EALDH1A1
SCHEMBL28372899 0.66 DAGLA (0.58) DRD2DRD3SMN1; SMN2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0031086-A1 Halogenated derivatives of imidazole-carboxylic acids, process for their preparation and their use as herbicides BAYER AG (DE) 1981-07-01 EP disclosed